Related Experiment Video

Updated: May 15, 2025

Intracerebroventricular Injection of Amyloid-β Peptides in Normal Mice to Acutely Induce Alzheimer-like Cognitive Deficits
08:01

Intracerebroventricular Injection of Amyloid-β Peptides in Normal Mice to Acutely Induce Alzheimer-like Cognitive Deficits

Published on: March 16, 2016

41.9K

Correction: An Anti-β-Amyloid vaccine for treating cognitive deficits in a mouse model of down syndrome

Pavel V Belichenko, Rime Madani, Lorianne Rey-Bellet

    Plos One
    |May 12, 2025
    PubMed

    Abstract:

    [This corrects the article DOI: 10.1371/journal.pone.0152471.].

    More Related Videos

    Stereotaxic Infusion of Oligomeric Amyloid-beta into the Mouse Hippocampus
    08:16

    Stereotaxic Infusion of Oligomeric Amyloid-beta into the Mouse Hippocampus

    Published on: June 17, 2015

    18.1K
    Neurodegeneration in an Animal Model of Chronic Amyloid-beta Oligomer Infusion Is Counteracted by Antibody Treatment Infused with Osmotic Pumps
    10:19

    Neurodegeneration in an Animal Model of Chronic Amyloid-beta Oligomer Infusion Is Counteracted by Antibody Treatment Infused with Osmotic Pumps

    Published on: August 14, 2016

    9.2K

    Related Experiment Videos

    Last Updated: May 15, 2025

    Intracerebroventricular Injection of Amyloid-β Peptides in Normal Mice to Acutely Induce Alzheimer-like Cognitive Deficits
    08:01

    Intracerebroventricular Injection of Amyloid-β Peptides in Normal Mice to Acutely Induce Alzheimer-like Cognitive Deficits

    Published on: March 16, 2016

    41.9K
    Stereotaxic Infusion of Oligomeric Amyloid-beta into the Mouse Hippocampus
    08:16

    Stereotaxic Infusion of Oligomeric Amyloid-beta into the Mouse Hippocampus

    Published on: June 17, 2015

    18.1K
    Neurodegeneration in an Animal Model of Chronic Amyloid-beta Oligomer Infusion Is Counteracted by Antibody Treatment Infused with Osmotic Pumps
    10:19

    Neurodegeneration in an Animal Model of Chronic Amyloid-beta Oligomer Infusion Is Counteracted by Antibody Treatment Infused with Osmotic Pumps

    Published on: August 14, 2016

    9.2K

    Related Concept Videos

    Alzheimer's Disease: Treatment01:22

    Alzheimer's Disease: Treatment

    133
    Alzheimer's Disease (AD), a neurodegenerative disorder, is pathologically identified by amyloid plaques and neurofibrillary tangles composed of tau protein. AD pharmacotherapy aims to manage cognitive symptoms, delay disease progression, and treat behavioral symptoms. The treatment is primarily symptomatic and palliative, with no definitive disease-modifying therapy available. Cholinesterase inhibitors, including donepezil (Aricept), rivastigmine (Exelon), and galantamine (Razadyne), are...
    133

    Articles linked to this work by shared authors, journal, and citation graph.

    Elimination of tau tangles and soluble aggregates with the small molecule ACI-16664 prevents neurodegeneration in vivo.

    Alzheimer's & dementia : the journal of the Alzheimer's Association·2026

    Preformed fibrils of α-synuclein rapidly activate LRRK2 on early endosomes, driving Rab5 phosphorylation and disrupting endolysosomal and synaptic function.

    NPJ Parkinson's disease·2026

    Chronic suppression of monoacylglycerol lipase restores adult neurogenesis in the septal but not the temporal DG in Ts65Dn mouse model of Down syndrome.

    Brain research bulletin·2026

    Drug Development.

    Alzheimer's & dementia : the journal of the Alzheimer's Association·2025

    Development of [18F]ACI-19626 as a first-in-class brain PET tracer for imaging TDP-43 pathology.

    Nature communications·2025

    Safety and immunogenicity of two Tau-targeting active immunotherapies, ACI-35.030 and JACI-35.054, in participants with early Alzheimer's disease: a phase 1b/2a, multicentre, double-blind, randomised, placebo-controlled study.

    EBioMedicine·2025

    Negative emotions concentrate while positive emotions diffuse in football fan rivalries.

    PloS one·2026

    Nationwide trends in dementia subtypes and in-hospital mortality among hospitalizations with type 2 diabetes in Spain, 2021-2024: A focus on sex disparities.

    PloS one·2026

    Influence of arteries, vein and placenta interactions on the blood flow in the human umbilical cord.

    PloS one·2026

    Prevalence and associated factors of sexually transmitted infections among unmarried undergraduate university students.

    PloS one·2026

    Methylene blue removal from water using chaya-derived biochar: Effect of metabolite extraction on adsorption.

    PloS one·2026

    Vascular anatomy of the right colon: A cadaveric study in a Vietnamese population with surgical implications.

    PloS one·2026

    Safety of Pulsed Field Ablation: Established Evidence, Emerging Risks, and Knowledge Gaps.

    Pacing and clinical electrophysiology : PACE·2026

    Clinical utility of LUMIPULSE plasma p-tau217 to identify amyloid positivity among candidates for amyloid-targeting treatments in a real-world cohort.

    Alzheimer's & dementia (Amsterdam, Netherlands)·2026

    Role of Gut Microbiome-derived Trimethylamine N-oxide and Short-chain Fatty Acids in Heart Failure Outcomes: A Narrative Review.

    Cardiovascular & hematological disorders drug targets·2026

    Risk of Respiratory Tract Infections with Asthma Biologics.

    The journal of allergy and clinical immunology. In practice·2026

    Botulinum Toxin in Children and Adolescents-A Comprehensive Review of Clinical Applications.

    Toxins·2026

    Potential Mechanisms Linking Excessive Testosterone to PMOS: Insights from Network Toxicology and Machine Learning.

    Metabolites·2026
    See all related articles
    JoVE
    x logofacebook logolinkedin logoyoutube logo
    ABOUT JoVE
    OverviewLeadershipBlogJoVE Help Center
    AUTHORS
    Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
    LIBRARIANS
    TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
    RESEARCH
    JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
    EDUCATION
    JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
    Terms & Conditions of Use
    Privacy Policy
    Policies
    Jove
    Visualize
    Contact Us