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Updated: Jun 16, 2025

Multi-timescale Microscopy Methods for the Characterization of Fluorescently-labeled Microbubbles for Ultrasound-Triggered Drug Release
Published on: June 12, 2021
Current developments in diverse biomaterial formulations for ultrasound-mediated drug delivery
Ji Won Nam1, Badrinathan Sridharan2, Juhyun Kang2
1Industry 4.0 Convergence Bionics Engineering, Pukyong National University, Busan 48513, Republic of Korea.
Abstract:
In this review, we focus on advances in drug delivery systems (DDSs) pertaining to modern therapeutics, with a particular emphasis on the role of ultrasound (US)-mediated drug delivery (UMDD). We highlight the need for advanced systems in response to several challenges, such as the diversity of pharmacological agents and individual patient variations, over traditional methodologies. We detail the mechanisms of UMDD (thermal and mechanical), and discuss various material formulations suitable for UMDD. We also discuss new perspectives on the potential of US to innovate drug delivery methodologies and improve patient outcomes to emphasize the importance of development to enhance treatment effectiveness.
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