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Efficacy and Safety of Reduced Port Surgery for Colorectal Cancer
Shoichi Fujii1, Yuma Suno1, Shingo Ito1
1Department of Surgery, Shonan Kamakura General Hospital, Kamakura City, Japan.
Background:
Reduced port surgery (RPS) for colorectal cancer has been associated with favorable cosmetic outcomes; however, its safety and efficacy are inconclusive. The purpose of this study is to clarify the efficacy and safety of laparoscopic RPS for colorectal cancer.
Methods:
A randomized controlled trial of laparoscopic multi-port surgery (MPS) and RPS for colorectal cancer except lower rectal cancer was conducted from 2014 to 2020. The eligibility criteria were elective surgery for clinical stages 0-III and D2 or D3 lymph node dissection. MPS was defined as 4- to 5-port and RPS as 1- to 2-port. Short- and long-term results and health-related quality of life (HRQOL) scores at 1 month and 1 year postoperatively were compared.
Results:
Ninety-one patients (46 MPS; 45 RPS) were analyzed. The short-term results (MPS: RPS), operative time, blood loss, and incidence of early complications did not differ. There was a significant difference in the length of postoperative stay (11:9 days, p = 0.034). The long-term results showed no differences in the 5-year overall survival rates and cancer-specific survival rates. Regarding HRQOL, there were no differences in the eight subscales and two summary scores at 1 month and 1 year postoperatively.
Conclusion:
Short- and long-term outcomes and HRQOL scores of RPS for colorectal cancer were similar to those of MPS. RPS may be a potential therapeutic option for colorectal cancer.
