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Patient rights in precision oncology: right treatment, right time, right dose, right order, right place

Elena Fountzilas1,2, Apostolia-Maria Tsimberidou3, Razelle Kurzrock4,5

  • 1Department of Medical Oncology, St Luke's Clinic, Thessaloniki, Greece. fountzila@oncogenome.gr.

Genome Medicine
|May 12, 2025
PubMed

Insights

Precision oncology offers individualized cancer care, moving beyond one-size-fits-all treatments. This approach faces challenges in implementation, requiring comprehensive strategies for better patient outcomes.

Area of Science:

  • Oncology
  • Genomics
  • Personalized Medicine

Background:

  • Precision oncology has shifted cancer care from generalized to individualized treatment strategies.
  • This paradigm shift aims to improve patient outcomes by tailoring therapies to specific molecular profiles.

Purpose of the Study:

  • To discuss the challenges in implementing personalized cancer treatments.
  • To explore comprehensive strategies for improving patient outcomes in precision oncology.
  • To consider factors beyond molecular profiles, including tumor complexity, quality of life, and diversity.

Main Methods:

  • This is a commentary discussing existing literature and clinical challenges.
  • Analysis of current trends and future directions in precision oncology implementation.
  • Synthesis of perspectives on integrating molecular data with patient-centered care.

Main Results:

  • Precision oncology implementation faces significant hurdles.
  • Addressing tumor complexity and individual molecular portfolios is crucial.
  • Integrating quality of life and diversity considerations is essential for equitable and effective care.

Conclusions:

  • Successful precision oncology requires overcoming implementation challenges.
  • Comprehensive strategies must address biological complexity and patient individuality.
  • Future efforts should prioritize holistic patient care, encompassing quality of life and diversity.
Keywords:
BiomarkersDosePrecision oncologySequenceTargeted treatmentsTrial decentralization

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