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Beyond the Basics: Recommended Approach to Severe Acute Pancreatitis Management in the Critical Care Setting

Zaid Alkaissy1, Kelli Kosako Yost2, Megan B Ghai2

  • 1Department of Medicine, Division of Gastroenterology and Hepatology, University of Arizona College of Medicine-Phoenix, Phoenix, AZ, USA.

Journal of Intensive Care Medicine
|May 13, 2025
PubMed

Insights

Severe acute pancreatitis (SAP) is a serious condition with high mortality. Advances in multidisciplinary care have reduced complications, but challenges remain in managing SAP.

Area of Science:

  • Gastroenterology
  • Critical Care Medicine
  • Surgical Management

Background:

  • Acute pancreatitis (AP) presents a global health challenge.
  • Approximately 20% of AP cases progress to severe forms with significant mortality (up to 40%).
  • Severe AP requires a multidisciplinary approach for effective management.

Purpose of the Study:

  • To review the management challenges in severe acute pancreatitis.
  • To discuss the outcomes associated with severe acute pancreatitis.
  • To highlight advances in treatment modalities for severe AP.

Main Methods:

  • This review synthesizes current literature on severe acute pancreatitis management.
  • Focuses on multidisciplinary team roles and treatment advancements.
  • Examines challenges and outcomes in severe AP cases.

Main Results:

  • Despite advancements, severe AP remains a complex condition.
  • Multidisciplinary care has improved outcomes, reducing morbidity and long-term complications to 20%.
  • Early hydration, nutrition, and pain control are crucial.

Conclusions:

  • Effective management of severe acute pancreatitis relies on a coordinated multidisciplinary team.
  • Continued research is needed to further improve outcomes for severe AP patients.
  • Addressing management challenges is key to reducing mortality and morbidity.

Keywords:
acute severe pancreatitiscritical care pancreatitislocal complications

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