Related Experiment Video
Updated: May 15, 2025

Author Spotlight: Advancements in Retroperitoneal Approach for Necrotizing Pancreatitis
Published on: March 15, 2024
Pediatric renal abscess: clinical analysis and literature review
Jianxin Sun1, Lina Shi2, Lezhen Ye1
1Department of Paediatrician, Women's and Children's Hospital of Ningbo University, Ningbo, China.
Insights
Pediatric renal abscesses present with atypical symptoms, often missed. Early diagnosis via imaging and prompt antibiotic treatment are crucial for preventing kidney damage in children.
Area of Science:
- Pediatric Nephrology
- Infectious Diseases
- Diagnostic Imaging
Background:
- Pediatric renal abscesses are severe infections with challenging diagnosis due to atypical symptoms.
- Delayed or inadequate treatment risks prolonged hospitalization and irreversible kidney damage.
Purpose of the Study:
- To analyze clinical characteristics of pediatric renal abscesses.
- To guide early diagnosis and timely, appropriate treatment strategies.
Main Methods:
- Retrospective analysis of 12 pediatric renal abscess cases (October 2018 - March 2023).
- Reviewed clinical data, laboratory tests, imaging studies (CT/MRU), and treatment outcomes.
Main Results:
- 12 cases (3 male, 9 female, 7 months-12 years) presented with fever, abdominal pain, and elevated inflammatory markers (WBC, CRP, PCT).
- Imaging revealed abscesses <3 cm; urine/blood cultures were negative.
- Treatment with cephalosporins +/- linezolid resulted in resolution within 10-21 days.
Conclusions:
- Pediatric renal abscesses exhibit atypical symptoms, necessitating high clinical suspicion.
- Elevated inflammatory markers and imaging (CT/MRU) are key for early diagnosis.
- Conservative antibiotic therapy is effective for small renal abscesses (<3 cm).
Background:
Pediatric renal abscesses is a severe infectious disease with a long treatment period. Due to atypical symptoms, there is a risk of delayed diagnosis, missed diagnosis, and misdiagnosis. Inadequate or incomplete treatment can lead to prolonged hospital stays, even Irreversible kidney damage. This study aimed to analyze the clinical characteristics of pediatric renal abscesses, aiming for early diagnosis and timely, appropriate treatment.
Methods:
A retrospective analysis was conducted on clinical manifestations, laboratory tests, imaging studies, and treatment data of 12 pediatric renal abscess cases treated in the Nephrology Department of our hospital from October 2018 to March 2023.
Results:
Among the 12 cases, there were 3 males and 9 females, aged between 7 months to 12 years. All cases were from urban areas, with fever being the primary symptom (100%), accompanied in some by abdominal pain and urinary frequency/pain. Clinical symptoms were atypical, with 91% showing elevated white blood cell count(WBC), a significant rise in neutrophil percentage, C-reactive protein (CRP), and a marked increase in procalcitonin (100%). significant elevation of urinary white blood cells in 83.3% of cases. Both urine and blood cultures were negative. All 12 cases underwent abdominal CT or Magnetic Resonance Urography (MRU), showing abscesses, all less than 3 cm. Treatment included third-generation cephalosporins, with the addition of linezolid in cases where the initial treatment was ineffective. Hospital stays ranged from 10 to 21 days. Follow-up MRU showed the disappearance of abscesses.
Conclusion:
Clinical symptoms of pediatric renal abscesses are atypical. Children with fever, accompanied by abdominal pain, and significant elevation in white blood cells, CRP, and PCT should be considered for renal abscess, and abdominal CT or MRU is recommended for early diagnosis. Conservative anti-infection treatment can yield good results for abscesses smaller than 3 cm.
Related Concept Videos
Kidney Structure
Factors Affecting Renal Clearance: Renal Impairment
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
Internal Anatomy of the Kidney
Anatomical Position and Dimensions
The kidneys are retroperitoneal organs positioned against the posterior abdominal wall on either side of the spine, roughly between the twelfth thoracic and third lumbar vertebrae. Each kidney is typically 10-12 cm long, 5-6 cm wide, and 3-4 cm thick, weighing about 150 grams.
Renal Cortex
The outermost region of the kidney is the...
Filtration and Urine Formation
External Anatomy of the Kidney
The kidneys are located in the retroperitoneal space on either side of the vertebral column, protected posteriorly by the 11th and 12th ribs. The right kidney sits slightly lower than the left owing to the presence of the liver...
Renal Tubule and Collecting Duct
Proximal Convoluted Tubule (PCT):
The PCT is the initial segment of the renal tubule, extending from the Bowman's capsule that encloses the glomerulus. Its convoluted structure and microvilli-lined cells increase the surface area for reabsorption. The PCT reabsorbs glucose, amino acids, sodium, and water from the filtrate, ensuring essential...

