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Noonan Syndrome and Heart Failure in a Postpartum Patient
Jose Alberto Domínguez-López1, Davina Desireé Teco-Mendoza2, Luis E Mendoza-Razo3
1Genetics, Universidad Autónoma de Chiapas, Instituto de Salud del Estado de Chiapas, Tuxtla Gutiérrez, MEX.
Abstract:
A 29-year-old postpartum woman with no prior Noonan syndrome diagnosis was admitted for recurrent chest pain, dyspnea, and palpitations. She had two adverse pregnancy outcomes, including a neonatal death due to perinatal asphyxia. Physical examination revealed characteristic facial features, and echocardiography confirmed biventricular failure, hypertrophic cardiomyopathy, and a 2.5 cm intracavitary thrombus in the left ventricle. She was treated with heart failure management, anticoagulation, and diuretics before being referred to a specialized cardiology center. This case highlights the challenges in diagnosing and managing cardiovascular complications in suspected Noonan syndrome.
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