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Updated: May 15, 2025

From Molecules to Materials: Engineering New Ionic Liquid Crystals Through Halogen Bonding
Published on: March 24, 2018
Dicarboxylate recognition based on ultracycle hosts through cooperative hydrogen bonding and anion-π interactions
Wen-Hui Mi1,2, Teng-Yu Huang1, Xu-Dong Wang1
1Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Molecular Recognition and Function, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, China.
Abstract:
The efficient binding of dicarboxylates represents an important yet challenging issue in supramolecular chemistry. In this study, we designed functional ultracycles as hosts to accommodate large organic dicarboxylate anions. These ultracycles were synthesized via a one-pot strategy starting from macrocyclic precursors. Host-dicarboxylate binding was investigated using 1H NMR titrations, revealing that B4aH exhibits strong binding affinities toward a series of dicarboxylates, with association constants reaching up to 6896 M-1. The selectivity for heptanedioate (C7 ) was attributed to cooperative hydrogen bonding, anion-π interactions, and a size-matching effect, as supported by DFT optimizations.
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