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Updated: May 15, 2025

High-Efficiency Generation of Antigen-Specific Primary Mouse Cytotoxic T Cells for Functional Testing in an Autoimmune Diabetes Model
Published on: August 16, 2019
Teplizumab: a promising intervention for delaying type 1 diabetes progression
Muhammad Rizwan Saleem1, Muhammad Talha Khan1
1Dow Medical College Bachelor of Medicine, Bachelor of Surgery (MBBS), Dow University of Health Sciences, Karachi, Sindh, Pakistan.
Abstract:
Type 1 diabetes (T1D) arises from an autoimmune attack on pancreatic beta cells, leading to a reliance on external insulin to maintain glucose levels. In recent years, research has increasingly focused on preventive strategies for individuals at high risk. A promising new intervention in this field is Teplizumab, the first approved disease-modifying therapy for T1D. Teplizumab is designed to delay progression to stage 3 T1D in adults and children aged 8 years and older who are diagnosed with stage 2 T1D.
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