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Post-infective malabsorption in the temperate zone.

R D Montgomery, I M Chesner

    Transactions of the Royal Society of Tropical Medicine and Hygiene
    |January 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

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    Post-infective malabsorption can occur in adults after acute enteritis, sometimes severely. This condition involves small bowel bacterial contamination and differs from tropical sprue due to better recovery rates.

    Area of Science:

    • Gastroenterology
    • Infectious Diseases
    • Internal Medicine

    Background:

    • Persistent bowel symptoms can follow acute enteritis.
    • Post-infectious sequelae are recognized in various clinical contexts.

    Purpose of the Study:

    • To investigate persistent bowel symptoms after acute enteritis in adults.
    • To characterize the features of post-infective malabsorption.

    Main Methods:

    • Investigated 37 adults with persistent bowel symptoms post-enteritis.
    • Assessed for intestinal malabsorption, jejunal mucosal abnormalities, and jejunal fluid bacterial cultures.
    • Correlated findings with travel history and folate levels.

    Main Results:

    • 26 out of 37 adults had intestinal malabsorption.

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  • Mild jejunal mucosal abnormalities were common; lymphocyte counts correlated with malabsorption severity.
  • Folate deficiency was prevalent in severe cases (over 80%); Enterobacteria cultured from jejunal fluid in 30%.

    • Conclusions:

    • Post-infective malabsorption occurs sporadically in adults in temperate climates and can be severe.
    • The condition involves small bowel contamination with Enterobacteria.
    • It is similar to tropical sprue but tends to resolve spontaneously more often.