Percutaneous VenusP-valve implantation in the paediatric population

Area of Science:

• Cardiovascular Medicine
• Interventional Cardiology
• Pediatric Cardiology

Background:

• Percutaneous pulmonary valve implantation is an alternative to surgery for right ventricular outflow tract conduits.
• The VenusP-valve shows efficacy in adults but its use in children is less documented.

Purpose of the Study:

• To evaluate the short- and medium-term outcomes of VenusP-valve implantation in pediatric patients.
• To assess the safety and feasibility of this transcatheter procedure in a younger population.

Main Methods:

• Retrospective review of patients under 18 years old who received a VenusP-valve.
• Data collected from June 2015 to February 2023 at a single institution.
• Follow-up included magnetic resonance imaging (MRI) for surveillance.

Main Results:

• Fifteen pediatric patients underwent successful VenusP-valve implantation for severe pulmonary regurgitation.
• Mean follow-up was 3.4 years.
• Significant reductions were observed in indexed right ventricular end-diastolic volume (p=0.004) and pulmonary regurgitation fraction (p=0.003).

Conclusions:

• VenusP-valve implantation is safe and feasible in the pediatric population.
• Medium-term results indicate a reduction in pulmonary regurgitation and right ventricular volume.
• This percutaneous option provides a promising alternative for pediatric pulmonary valve replacement.