[Effect of lactate on the effectiveness of glucose and succinate oxidation by myocardium homogenates]
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Updated: Jul 27, 2026

12:24
Methods for the Determination of Rates of Glucose and Fatty Acid Oxidation in the Isolated Working Rat Heart
Published on: September 28, 2016
Abstract:
Lactate (20 mM) was studied for its effect on the intensity of [1-6-14C] glucose and [1,4-14C] succinate oxidation by the rat myocardial homogenates. It is established that lactate induces specific suppression of aerobic glucose oxidation. A moderate reduction of the succinate and lactate oxidation in their combined incubation is of a non-specific character.

