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Streptococcus pyogenes Surveillance Through Surface Swab Samples to Track the Emergence of Streptococcal Toxic Shock
Dhammika Leshan Wannigama1,2,3,4,5, Mohan Amarasiri6, Phatthranit Phattharapornjaroen2,7,8
1Department of Infectious Diseases, Faculty of Medicine, Yamagata University and Yamagata University Hospital, Yamagata, Japan.
The Journal of Infectious Diseases
|May 13, 2025
Abstract:
Japan recently experienced a record surge in streptococcal toxic shock syndrome. Our environmental surveillance study reveals that Streptococcus pyogenes persists seasonally, peaking in autumn and winter in rural Japan. The dominant emm1 M1UK sublineage and csrS mutations heighten virulence, highlighting the urgent need for targeted surveillance and interventions.
Keywords:
Streptococcus pyogenescsrS mutationsemm1JapanM1UKSTSSgroup A Streptococcus (GAS)necrotizing fasciitisrural JapanspeBspy1258streptococcal toxic shock syndrome
