99m Tc-PSMA Scintigraphy in Splenic Hemangioma

A 67-year-old man was referred for initial staging of prostate adenocarcinoma (Gleason score 4+3, 7/12 cores positive). A 99m Tc-PSMA scintigraphy revealed localized uptake in the right prostate lobe (miTNM: T 2m N 0 M 0 , and PRIMARY score: 5) and increased uptake in a hypo-dense splenic lesion (PSMA-RADS-3C), which was subsequently confirmed as a hemangioma on further evaluations. This case underscores the potential for false-positive 99m Tc-PSMA uptake in splenic hemangiomas, highlighting the importance of considering this possibility in clinical practice.