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Updated: May 15, 2025
A Practical Guide for the Production and PET/CT Imaging of 68Ga-DOTATATE for Neuroendocrine Tumors in Daily Clinical Practice
Published on: April 17, 2019
False-positive Uptake in Splenic Hamartoma on 68 Ga-DOTATATE PET/CT
Chenxi Wu1, Julia W Foster2, Shahein Tajmir1
1Department of Radiology and Imaging Science, Division of Nuclear Medicine and Molecular Imaging.
Abstract:
68 Ga-DOTATATE is not completely specific for neuroendocrine tumors, and a wide range of benign and malignant tumors may reveal high uptake of 68 Ga-DOTATATE on PET scan. Spleen hamartoma is a rare benign solid lesion of the spleen, composed of a mixture of normal splenic structures. Here we present a case of a 49-year-old woman who underwent a 68Ga-DOTATATE PET/CT scan for complete staging of a duodenal neuroendocrine tumor, and it incidentally demonstrated intense radiotracer uptake in a splenic lesion, with surgical pathology demonstrating a splenic hamartoma.
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