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High Life's Essential 8 score is associated with lower aortic valve calcification
Man Gui1, Shuohua Chen2, Yihao Qi1
1School of Nursing and Rehabilitation, North China University of Science and Technology, Tangshan, Hebei, China.
A high Life's Essential 8 (LE8) score is linked to reduced aortic valve calcification (AVC) risk. Adopting healthy lifestyle behaviors can lower the likelihood of developing AVC.
Area of Science:
- Cardiovascular Health
- Preventive Cardiology
- Public Health
Background:
- Aortic valve calcification (AVC) is a significant risk factor for cardiovascular disease.
- Life's Essential 8 (LE8) is a comprehensive measure of cardiovascular health.
- The relationship between LE8 and AVC risk requires further investigation.
Purpose of the Study:
- To examine the association between Life's Essential 8 (LE8) and Aortic Valve Calcification (AVC).
- To determine if a high LE8 score can mitigate the risk of developing AVC.
Main Methods:
- Analysis of data from 30,561 participants in the Kailuan cohort.
- Utilized multifactorial logistic regression to assess the LE8-AVC relationship.
- Conducted subgroup analyses and evaluated individual LE8 components' impact on AVC.
Main Results:
- A higher LE8 score was significantly associated with a lower prevalence of AVC (P<0.001).
- Individuals with moderate and high LE8 scores showed a 34% and 63% reduced risk of AVC, respectively.
- Diet, exercise, BMI, blood lipids, glucose, and blood pressure were key LE8 components associated with reduced AVC risk.
Conclusions:
- Elevated LE8 scores correlate with a diminished risk of aortic valve calcification.
- Promoting healthy lifestyle behaviors, as measured by LE8, offers a potential strategy for AVC prevention.
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