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Overwork is linked to structural brain changes, particularly in areas affecting executive function and emotional regulation. This study highlights potential neurological risks of prolonged working hours for healthcare professionals.

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Area of Science:

  • Neuroscience
  • Occupational Health
  • Brain Imaging

Background:

  • Prolonged working hours are prevalent in healthcare.
  • Understanding the neurological impact of overwork is crucial for worker well-being.

Purpose of the Study:

  • To investigate the effects of overwork on brain structure.
  • To assess the impact of prolonged working hours on cognitive and emotional health.
  • To provide evidence for potential neurological risks associated with overwork.

Main Methods:

  • 110 healthcare workers were divided into overworked (≥52 hours/week) and non-overworked groups.
  • Voxel-based morphometry (VBM) and atlas-based analysis were used to assess brain volume differences.
  • General linear models and correlation analyses were employed to examine relationships between working hours and brain structure.

Main Results:

  • Overworked individuals showed significant brain structure changes in regions vital for executive function and emotional regulation.
  • A 19% increase in left caudal middle frontal gyrus volume was observed in the overworked group.
  • VBM identified increased volume in 17 regions, including the middle frontal gyrus, insula, and superior temporal gyrus, with a positive correlation between working hours and these changes.

Conclusions:

  • Overwork is associated with structural brain changes, particularly in areas influencing cognition and emotion.
  • This study offers novel neurobiological evidence linking extended work hours to alterations in brain structure.
  • Further research is needed to understand the long-term cognitive and emotional consequences of overwork.