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Updated: May 15, 2025
Retinal and Choroidal Thickness Changes in Populations with Helicobacter pylori Infection by Swept-Source Optical Coherence Tomography
Published on: November 1, 2024
Choroidal vascular alterations in patients with Helicobacter pylori gastritis
1Department of Ophthalmology, KTO Karatay University Medicana Konya Hospital, Konya, Turkiye.
Background And Study Aims:
This study aims to examine the impact of Helicobacter pylori (H. pylori) gastritis, a condition that induces chronic inflammation in the body, on subfoveal choroidal thickness (SFCT) and choroidal vascular index (CVI) measurements.
Patients And Methods:
In this prospective study, data were collected from 76 patients who visited the gastroenterology clinic, had their H. pylori diagnosis confirmed through gastric biopsy, and had not yet received treatment. An additional 76 age- and gender-matched healthy individuals formed the control group. Subfoveal choroidal thickness (SFCT) was measured using enhanced depth imaging optical coherence tomography (EDI-OCT) (Spectralis, Heidelberg Engineering, Heidelberg, Germany). CVI measurements were obtained by dividing the subfoveal choroidal area in the EDI-OCT images into luminal and stromal areas using the image binarization technique.
Results:
The mean SFCT was 359.14 ± 24.23 µm in the H. pylori-positive group and 353.62 ± 12.78 µm in the control group, with no statistically significant difference between the groups (p = 0.782). Similarly, the choroidal vascular index (CVI) was 0.63 in the H. pylori group and 0.62 in the control group, with no significant difference observed (p = 0.08).
Conclusion:
Results indicate that SFCT and CVI measurements do not undergo significant changes during the active phase of H. pylori infection compared to the control group.
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