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[Pancreaticoduodenectomy with Pancreaticogastric Anastomosis for Jehovah's Witness Patients]

Kenjiro Kitasato1, Taku Akahoshi, Ippei Murata

  • 1Dept. of Surgery, Chiba Tokushukai Hospital.

Gan to Kagaku Ryoho. Cancer & Chemotherapy
|May 13, 2025
PubMed

Insights

This study shows that pancreaticoduodenectomy with pancreaticogastric anastomosis is a safe surgical option for Jehovah's Witnesses patients, avoiding blood transfusions and achieving good outcomes.

Area of Science:

  • Surgical Oncology
  • Gastroenterology
  • Transfusion Medicine

Background:

  • Jehovah's Witnesses decline blood transfusions, limiting surgical options.
  • Pancreaticoduodenectomy carries a high risk of bleeding, especially with pancreatic fistulas.
  • Hospital policy supports surgical care for Jehovah's Witnesses when feasible.

Purpose of the Study:

  • To evaluate the safety and efficacy of pancreaticoduodenectomy with pancreaticogastric anastomosis in Jehovah's Witnesses.
  • To assess the feasibility of this procedure without blood transfusions.

Main Methods:

  • Four Jehovah's Witnesses patients underwent pancreaticoduodenectomy between November 2017 and May 2024.
  • Procedures included reconstructions with gastro-pancreatic anastomosis.
  • Patients had diagnoses of IPMC, ampullary carcinoma, cholangiocarcinoma, and duodenal carcinoma.

Main Results:

  • All four patients completed the procedure without requiring blood transfusions.
  • Average operation time was 514 minutes with 290 mL blood loss.
  • One patient developed an intra-abdominal abscess; no hemorrhagic complications or in-hospital deaths occurred.

Conclusions:

  • Pancreaticoduodenectomy with pancreaticogastric anastomosis is an acceptable surgical approach for Jehovah's Witnesses.
  • The technique minimizes short-term fatal complications in this patient population.
Abstract

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