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Blockchain enabled collective and combined deep learning framework for COVID19 diagnosis
Sudhakar Periyasamy1, Prabu Kaliyaperumal1, Manikandan Thirumalaisamy2
1School of Computer Science and Engineering, Galgotias University, 203201, Delhi NCR, India.
Scientific Reports
|May 13, 2025
Summary
A new AI model, CLCD-Block, uses blockchain for secure, decentralized COVID-19 diagnosis. It achieves over 97% accuracy on CT scans, improving upon traditional methods by protecting patient privacy.
Area of Science:
- Medical Imaging
- Artificial Intelligence
- Blockchain Technology
Background:
- The rapid spread of SARS-CoV-2 necessitates advanced diagnostic tools for COVID-19.
- Conventional AI diagnostic models face challenges with centralized data, complexity, and privacy concerns, hindering global data sharing.
- There is a critical need for secure, collaborative diagnostic frameworks that balance accuracy with data protection.
Purpose of the Study:
- To introduce a novel framework, the Combined Learning Collective Deep Learning Blockchain Model (CLCD-Block), for secure and accurate COVID-19 diagnosis.
- To address the limitations of centralized data storage and training in AI-driven medical diagnostics.
- To develop a model that enhances data privacy and facilitates secure global data exchange.
Main Methods:
- The CLCD-Block framework integrates blockchain technology with a combined learning paradigm for decentralized AI training.
- A hybrid capsule learning network is employed for accurate diagnostic predictions using lung CT images.
- The model aggregates data from multiple institutions, ensuring secure distribution and reduced complexity.
Main Results:
- The CLCD-Block model demonstrated superior diagnostic performance, achieving an accuracy exceeding 97% on lung CT images.
- On four benchmark datasets, the model achieved high metrics: up to 98.79% Precision, 98.84% Recall, 98.79% Specificity, 98.81% F1-Score, and 98.71% Accuracy.
- The framework effectively balances diagnostic accuracy with robust privacy protection.
Conclusions:
- The CLCD-Block framework offers a secure, decentralized, and accurate solution for COVID-19 diagnosis.
- This model's adaptability extends to other healthcare applications, including chronic disease diagnosis and infectious outbreak monitoring.
- Future research will focus on enhancing scalability and real-time performance for broader healthcare dataset integration.

