Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The DNA Helix01:16

The DNA Helix

137.2K
Overview
137.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

DNA StairLoop: enabling high-fidelity data recovery and robust error correction in DNA-based data storage.

Nature communications·2025
Same author

Clover: tree structure-based efficient DNA clustering for DNA-based data storage.

Briefings in bioinformatics·2022
Same author

IoU Regression with H+L-Sampling for Accurate Detection Confidence.

Sensors (Basel, Switzerland)·2021
Same author

Probiotic safety in pregnancy: a systematic review and meta-analysis of randomized controlled trials of Lactobacillus, Bifidobacterium, and Saccharomyces spp.

Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC·2009
Same author

An approximation algorithm for the minimum breakpoint linearization problem.

IEEE/ACM transactions on computational biology and bioinformatics·2009
Same author

Evaluation of preoperative intra-aortic balloon pump in coronary patients with severe left ventricular dysfunction undergoing OPCAB surgery: early and mid-term outcomes.

Journal of cardiothoracic surgery·2009
Same journal

Systematic bottom-up coarse-graining of hydrated excess proton transport across scales.

Nature computational science·2026
Same journal

Gaining biological insights through supervised data visualization.

Nature computational science·2026
Same journal

The inequalities of GPU access.

Nature computational science·2026
Same journal

Social technologies need societal alignment.

Nature computational science·2026
Same journal

The Quantum Optimization Benchmarking Library.

Nature computational science·2026
Same journal

Setting benchmarks for practical quantum utility of combinatorial optimization.

Nature computational science·2026
See all related articles

Related Experiment Video

Updated: May 15, 2025

Databases to Efficiently Manage Medium Sized, Low Velocity, Multidimensional Data in Tissue Engineering
09:43

Databases to Efficiently Manage Medium Sized, Low Velocity, Multidimensional Data in Tissue Engineering

Published on: November 22, 2019

6.2K

DNA data storage for biomedical images using HELIX.

Guanjin Qu1, Zihui Yan2,3, Xin Chen1,3

  • 1Center for Applied Mathematics, Tianjin University, Tianjin, P. R. China.

Nature Computational Science
|May 13, 2025
PubMed
Summary
This summary is machine-generated.

We developed HELIX, a DNA data storage system for biomedical images. It uses novel compression and error correction for efficient, high-quality storage and retrieval of complex medical image data.

More Related Videos

Hi-C: A Method to Study the Three-dimensional Architecture of Genomes.
22:27

Hi-C: A Method to Study the Three-dimensional Architecture of Genomes.

Published on: May 6, 2010

408.6K
Structure of HIV-1 Capsid Assemblies by Cryo-electron Microscopy and Iterative Helical Real-space Reconstruction
12:38

Structure of HIV-1 Capsid Assemblies by Cryo-electron Microscopy and Iterative Helical Real-space Reconstruction

Published on: August 9, 2011

17.4K

Related Experiment Videos

Last Updated: May 15, 2025

Databases to Efficiently Manage Medium Sized, Low Velocity, Multidimensional Data in Tissue Engineering
09:43

Databases to Efficiently Manage Medium Sized, Low Velocity, Multidimensional Data in Tissue Engineering

Published on: November 22, 2019

6.2K
Hi-C: A Method to Study the Three-dimensional Architecture of Genomes.
22:27

Hi-C: A Method to Study the Three-dimensional Architecture of Genomes.

Published on: May 6, 2010

408.6K
Structure of HIV-1 Capsid Assemblies by Cryo-electron Microscopy and Iterative Helical Real-space Reconstruction
12:38

Structure of HIV-1 Capsid Assemblies by Cryo-electron Microscopy and Iterative Helical Real-space Reconstruction

Published on: August 9, 2011

17.4K

Area of Science:

  • Biotechnology
  • Bioinformatics
  • Data Science

Background:

  • Biomedical images require significant storage capacity over long durations.
  • Current DNA data storage methods are not optimized for specialized biomedical image retrieval.
  • A dedicated system is needed to address the unique challenges of storing and accessing biomedical image data in DNA.

Purpose of the Study:

  • To propose HELIX, a novel DNA-based data storage system specifically designed for biomedical images.
  • To develop advanced algorithms for efficient compression, error correction, and image restoration within the DNA storage framework.
  • To demonstrate the feasibility and effectiveness of HELIX for storing and retrieving complex biomedical image data.

Main Methods:

  • Developed a specialized image-compression algorithm optimized for biomedical image characteristics, ensuring high compression ratios and error resilience.
  • Implemented an error-correcting encoding algorithm that negates the need for indexing, thereby improving storage density and decoding efficiency.
  • Utilized a deep learning-based image repair algorithm for predictive restoration of any partially corrupted or missing image data blocks.

Main Results:

  • Successfully stored two spatiotemporal genomics images using the HELIX system in in vitro experiments.
  • Achieved a high image quality of 97.20% after the sequencing and retrieval process.
  • Demonstrated robust error tolerance and efficient data recovery, even with potential data loss.

Conclusions:

  • HELIX presents a viable and efficient DNA data storage solution tailored for the demands of biomedical imaging.
  • The system's integrated compression, error correction, and restoration capabilities offer significant advantages over generic storage methods.
  • This approach paves the way for long-term, high-density archival of critical biomedical image data, crucial for research and clinical applications.