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Related Concept Videos

What is Gene Expression?01:42

What is Gene Expression?

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Overview
Gene expression is the process in which DNA directs the synthesis of functional products, that is, proteins. Cells can regulate gene expression at various stages. It allows organisms to generate different cell types and enables cells to adapt to internal and external factors.
Genetic Information Flows from DNA to RNA to Protein
A gene is a stretch of DNA that serves as the blueprint for functional RNAs and proteins. Since DNA is made up of nucleotides and proteins consist of amino...
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Cell Specific Gene Expression01:58

Cell Specific Gene Expression

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Multicellular organisms contain a variety of structurally and functionally distinct cell types, but the DNA in all the cells originated from the same parent cells. The differences in the cells can be attributed to the differential gene expression. Liver cells, whose functions include detoxification of blood, production of bile to metabolize fats, and synthesis of proteins essential for metabolism, must express a specific set of genes to perform their functions. Gene expression also varies with...
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DNA Microarrays02:34

DNA Microarrays

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Microarrays are high-throughput and relatively inexpensive assays that can be automated to analyze large quantities of data at a time. They are used in genome-wide studies to compare gene or protein expression under two varied conditions, such as healthy and diseased states. Microarrays consist of glass or silica slides on which probe molecules are covalently attached through surface functionalization. Most commonly, the slides are prepared through the chemisorption of silanes to silica...
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Genomic DNA in Eukaryotes00:58

Genomic DNA in Eukaryotes

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Eukaryotes have large genomes compared to prokaryotes. To fit their genomes into a cell, eukaryotic DNA is packaged extraordinarily tightly inside the nucleus. To achieve this, DNA is tightly wound around proteins called histones, which are packaged into nucleosomes that are joined by linker DNA and coil into chromatin fibers. Additional fibrous proteins further compact the chromatin, which is recognizable as chromosomes during certain phases of cell division.
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Genomics02:02

Genomics

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Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
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Reporter Genes02:11

Reporter Genes

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Reporter genes are a type of protein-coding gene that are often tagged to a gene of interest. Once inside a target cell, reporter genes usually produce visually identifiable characteristics like fluorescence and luminescence when expressed along with the gene of interest. Thus, reporter genes “report” the presence or absence of genes of interest in an organism, determine the gene expression pattern, or track the physical location of a DNA segment or protein in the cell.
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Related Experiment Video

Updated: May 17, 2025

Comprehensive Workflow for the Genome-wide Identification and Expression Meta-analysis of the ATL E3 Ubiquitin Ligase Gene Family in Grapevine
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Comprehensive Workflow for the Genome-wide Identification and Expression Meta-analysis of the ATL E3 Ubiquitin Ligase Gene Family in Grapevine

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GEDG: gene expression database of grape.

Wen Sun1, Siyu Chen2, Lina Tan1

  • 1Laboratory of Modern Biotechnology, School of Forestry and Landscape Architecture, Anhui Agricultural University, Hefei, China.

BMC Plant Biology
|May 13, 2025
PubMed
Summary
This summary is machine-generated.

The Gene Expression Database of Grape (GEDG) provides comprehensive RNA-seq data for grape varieties, aiding research into stress responses and development. This resource enhances understanding of grapevine biology and agricultural applications.

Keywords:
DatabaseGEDGGrapeRNA-seqStress

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Area of Science:

  • Plant Science
  • Genomics
  • Bioinformatics

Background:

  • Grapes are ancient, nutritionally rich fruits vital to global economies.
  • Abiotic and biotic stresses critically affect grapevine growth and reproduction.
  • RNA-sequencing (RNA-Seq) is essential for studying gene expression under stress and developmental conditions.

Purpose of the Study:

  • To develop a comprehensive online database for grape gene expression profiles and traits.
  • To optimize the utilization and accessibility of grape transcriptome data for research.
  • To enhance the understanding of stress responses in grapevines.

Main Methods:

  • Development of the Gene Expression Database for Grapes (GEDG).
  • Integration of RNA-Seq data covering 9 abiotic stresses, biotic stresses, and developmental stages.
  • Inclusion of 32 stress-related, 20 growth/development-related, and 1 ploidy dataset.

Main Results:

  • GEDG offers a centralized resource for grape transcriptome and trait data.
  • The database facilitates in-depth analysis of gene expression under various stress conditions.
  • It provides a valuable tool for exploring grapevine genetic responses.

Conclusions:

  • The Gene Expression Database of Grape (GEDG) is a free, publicly accessible platform.
  • It offers a comprehensive collection of grape genetic expression profiles from RNA-seq data.
  • GEDG supports researchers in advancing grape science and breeding: https://www.gedg-vitis.cn/index.html.