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Complete Hydatiform Mole with a Coexisting Living Fetus: A Case Report
Irene Piccolotti1, Silvia Zago2, Maria Paola Bonasoni3
1Unit of Obstetrics and Gynecology, Azienda Ospedaliero-Universitaria di Ferrara, 44122 Ferrara, Italy.
Healthcare (Basel, Switzerland)
|May 14, 2025
Summary
This case study highlights a successful pregnancy with complete hydatiform mole with coexistent fetus (CHMCF), resulting in a healthy baby. Careful prenatal monitoring and postpartum follow-up are crucial for managing this rare obstetric complication.
Area of Science:
- Reproductive Medicine
- Maternal-Fetal Medicine
- Genetics
Background:
- Gestational trophoblastic diseases (GTD) include hydatiform moles (HMs), arising from conception errors causing abnormal chromosomal makeup.
- Complete hydatiform mole (CHM) involves a paternally derived diploid karyotype in an empty oocyte, characterized by villous degeneration and elevated beta-hCG.
- CHM with coexistent fetus (CHMCF) is rare, carries high risks of malignancy and complications like bleeding, preeclampsia, and fetal demise.
