Clinical Trial Awareness, Perceptions, and Participation Among Cancer Patients in Saudi Arabia

Area of Science:

• Oncology
• Clinical Research
• Public Health

Background:

• Clinical trials are vital for advancing cancer treatment and therapies.
• Patient participation in clinical trials is notably low in Saudi Arabia and the Middle East.
• Understanding patient perspectives is key to improving enrollment rates.

Purpose of the Study:

• To assess Saudi cancer patients' awareness, perceptions, and willingness to join clinical trials.
• To identify significant barriers hindering patient enrollment in cancer clinical trials within Saudi Arabia.

Main Methods:

• A cross-sectional survey was conducted using self-administered questionnaires.
• The study included 201 Saudi cancer patients (age ≥14) via email and social media.
• Data analysis involved SPSS and chi-square tests to identify associations.

Main Results:

• Moderate awareness (51.2%) of clinical trials was observed, with social media and healthcare providers as key sources.
• Fear of side effects (82.6%) and lack of information (42.8%) were primary barriers.
• While only 5.5% had prior experience, 35.3% were willing to enroll if recommended by a physician.

Conclusions:

• Targeted educational initiatives are needed to boost awareness and trust in clinical trials among Saudi cancer patients.
• Addressing concerns about side effects and information gaps can significantly improve participation.
• Enhanced patient enrollment will accelerate cancer research and treatment advancements in the region.