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Increased Musculoskeletal Surgery Rates During Diagnostic Delay in Psoriatic Arthritis: A Retrospective Cohort Study
Servet Yolbas1, İlyas Gündüz2, Mahmut Kara2
1Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, İnönü University, Malatya 44280, Turkey.
Diagnostics (Basel, Switzerland)
|May 14, 2025
Summary
Psoriatic arthritis (PsA) patients undergo more musculoskeletal surgeries during delayed diagnosis. Early PsA diagnosis may reduce surgery rates and healthcare costs.
Area of Science:
- Rheumatology
- Orthopedic Surgery
Background:
- Delayed diagnosis of psoriatic arthritis (PsA) leads to severe health issues.
- Musculoskeletal (MSK) surgery rates may increase during the diagnostic delay in PsA.
Purpose of the Study:
- To compare MSK surgery frequency in PsA patients during diagnostic delay versus post-diagnosis.
- To investigate the impact of early PsA diagnosis on surgical intervention rates.
Main Methods:
- Retrospective cohort study of PsA patients meeting CASPAR criteria.
- Analysis of MSK surgeries during the pre-diagnosis symptomatic period (diagnostic delay) and post-diagnosis.
- Calculation of annual surgery rates for both periods.
Main Results:
- 84 PsA patients were included, with a mean diagnostic delay of 7.49 years.
- 27.4% of patients had at least one MSK surgery during the diagnostic delay period.
- Significantly higher annual MSK surgery rates were observed during the diagnostic delay compared to the post-diagnosis period (p=0.001).
Conclusions:
- PsA patients experienced a reduction in MSK surgery rates after diagnosis.
- Unmanaged inflammatory symptoms during diagnostic delay may lead to avoidable MSK surgeries.
- Early PsA diagnosis can potentially decrease MSK surgery rates and associated healthcare expenditures.

