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Updated: May 15, 2025

A New Toolkit for Evaluating Gene Functions using Conditional Cas9 Stabilization
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Conditional Control of CRISPR/Cas9 Function by Chemically Modified Oligonucleotides.

Liangliang Wang1,2, Yan Liu2, Hongjun Song2

  • 1School of Biological and Pharmaceutical Engineering, Lanzhou Jiaotong University, Lanzhou 730070, China.

Molecules (Basel, Switzerland)
|May 14, 2025
PubMed
Summary

Chemically modified guide RNAs offer precise control over CRISPR gene editing. These innovations enhance precision and efficiency, paving the way for safer gene therapies and advanced functional genomics research.

Keywords:
CRISPR/Cas9chemical modificationconditional controlgene editingguide RNA (gRNA)

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