Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

67
Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
67
Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding01:15

Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding

48
Enteral nutrition encompasses various methods of delivering nutrition directly to the gastrointestinal (GI) tract, bypassing traditional oral intake. It is particularly beneficial for patients who cannot eat by mouth but have a functioning digestive system. Key methods include nasointestinal feeding, gastrostomy, and jejunostomy, each suited to different clinical scenarios based on the patient's needs and condition.
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...
48
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

251
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
251
Appendicitis-II: Diagnostic Studies and Management01:29

Appendicitis-II: Diagnostic Studies and Management

52
Diagnosing and managing appendicitis requires a structured and comprehensive approach that spans from initial assessment to postoperative care. Here is an overview of the process:
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
52
Inflammatory Bowel Disease IV: Pharmacological Management01:29

Inflammatory Bowel Disease IV: Pharmacological Management

80
Upon diagnosis, managing Inflammatory Bowel Disease (IBD) involves addressing several crucial aspects. The primary goals include resting the bowel, correcting malnutrition, and providing symptomatic relief. Resting the bowel may consist of medications to reduce inflammation and promote healing. Correcting malnutrition is essential, often requiring dietary adjustments and nutritional supplements. Symptomatic relief aims to ease pain, diarrhea, and other discomforts in IBD.
Pharmacologic...
80
Irritable Bowel Syndrome III: Medical and Nursing Management01:30

Irritable Bowel Syndrome III: Medical and Nursing Management

123
Managing Irritable Bowel Syndrome (IBS) involves a multifaceted approach, including lifestyle modifications, dietary changes, and medication.
123

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Mechanical complications after central venous catheter repair: A case series.

Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition·2026
Same author

Long-term liver outcomes after metabolic surgery in compensated cirrhosis due to metabolic dysfunction-associated steatohepatitis.

Nature medicine·2025
Same author

Robotic versus open mini-incision living donor nephrectomy: Single centre experience.

The international journal of medical robotics + computer assisted surgery : MRCAS·2024
Same author

Administration of 4% tetrasodium EDTA lock solution and central venous catheter complications in high-risk pediatric patients with intestinal failure: A retrospective cohort study.

JPEN. Journal of parenteral and enteral nutrition·2024
Same author

Fat malabsorption in short bowel syndrome: A review of pathophysiology and management.

Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition·2024
Same author

Direct thrombin inhibitors fail to reverse the negative effects of heparin on lung growth and function after murine left pneumonectomy.

American journal of physiology. Lung cellular and molecular physiology·2023

Related Experiment Video

Updated: May 15, 2025

Tissue Engineering of the Intestine in a Murine Model
08:45

Tissue Engineering of the Intestine in a Murine Model

Published on: December 1, 2012

14.9K

Updates in Intestinal Failure Management.

Sarah Z Wang1, Elizabeth L O'Daniel1

  • 1Department of Surgery, Boston Children's Hospital, Harvard Medical School, 300 Longwood Ave, Boston, MA 02115, USA.

Journal of Clinical Medicine
|May 14, 2025
PubMed
Summary

Short bowel syndrome (SBS) is a malabsorptive condition linked to intestinal failure (IF). Management requires a multidisciplinary approach combining nutrition, medication, and surgery for improved outcomes.

Keywords:
intestinal failureintestinal rehabilitationmalabsorptionnutritionshort bowel syndrome

More Related Videos

Murine Ileocolic Bowel Resection with Primary Anastomosis
08:49

Murine Ileocolic Bowel Resection with Primary Anastomosis

Published on: October 29, 2014

16.3K
Small Bowel Transplantation In Mice
36:30

Small Bowel Transplantation In Mice

Published on: August 20, 2007

13.7K

Related Experiment Videos

Last Updated: May 15, 2025

Tissue Engineering of the Intestine in a Murine Model
08:45

Tissue Engineering of the Intestine in a Murine Model

Published on: December 1, 2012

14.9K
Murine Ileocolic Bowel Resection with Primary Anastomosis
08:49

Murine Ileocolic Bowel Resection with Primary Anastomosis

Published on: October 29, 2014

16.3K
Small Bowel Transplantation In Mice
36:30

Small Bowel Transplantation In Mice

Published on: August 20, 2007

13.7K

Area of Science:

  • Gastroenterology
  • Nutrition Science
  • Surgical Science

Background:

  • Short bowel syndrome (SBS) is a malabsorptive condition caused by reduced functional small intestinal length.
  • Intestinal failure (IF) is defined as insufficient intestinal mass for life support, requiring parenteral nutrition for at least 60 days.
  • IF often stems from intestinal resection due to conditions like necrotizing enterocolitis in children and Crohn's disease in adults.

Purpose of the Study:

  • To provide a comprehensive overview of intestinal failure (IF) and its management.
  • To highlight the multifaceted nature of IF, encompassing medical, surgical, and nutritional aspects.
  • To emphasize the importance of an interdisciplinary approach in managing IF patients.

Main Methods:

  • Review of current medical literature and clinical practices related to SBS and IF.
  • Discussion of established and emerging therapeutic strategies, including nutritional support, pharmacotherapy, and surgical interventions.
  • Emphasis on the collaborative care model involving various medical specialists and support staff.

Main Results:

  • Clinical manifestations of IF include diarrhea, growth failure, bacterial overgrowth, and vitamin deficiencies.
  • Nutritional rehabilitation is central to IF management.
  • Medical management includes tailored nutrition, GLP-2 agonists, and symptom-management drugs; surgical options focus on preserving length and continuity; distraction enterogenesis is an experimental therapy.

Conclusions:

  • Effective management of IF necessitates an individualized, interdisciplinary approach.
  • A combination of nutritional, medical, and surgical strategies is often required to optimize patient outcomes.
  • Ongoing research and development, including experimental therapies, aim to further improve the treatment of IF.