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[Morphologic changes in the nervous system in acute carbophos poisoning]
Zhurnal Nevropatologii I Psikhiatrii Imeni S.S. Korsakova (Moscow, Russia : 1952)
|January 1, 1985
Summary
Acute oral carbophos intoxication causes significant nervous system damage. Morphological examinations reveal vascular changes, cellular abnormalities, and demyelination in the central and peripheral nervous systems.
Area of Science:
- Neuropathology
- Toxicology
Context:
- Acute oral intoxication with carbophos (an organophosphate pesticide)
- Morphological examination of nervous system tissue
Purpose:
- To investigate the neuropathological effects of acute carbophos poisoning.
Summary:
- Vascular changes observed include congestive plethora, perivascular edema, and microfocal hemorrhages.
- Cellular abnormalities included acute swelling, ischemic, and hydropic alterations.
- Pathomorphology of nerve fibers showed secondary demyelination in the internal capsule, spinal cord, and peripheral nerves.
Impact:
- Provides detailed morphological insights into carbophos neurotoxicity.
- Highlights the severe impact of organophosphate poisoning on nervous system structures.