[Morphologic changes in the nervous system in acute carbophos poisoning]

The nervous system of 13 patients who died of an acute oral intoxication with carbophos was subjected to morphological examinations. Vascular changes were expressed as congestive plethora, perivascular edema and microfocal hemorrhages. Cellular abnormalities mainly included acute swelling, severe ischemic and hydropic alterations. Pathomorphology of the fibers was manifested in foci of secondary demyelinization in the internal capsule, lateral columns of the spinal cord and the peripheral nerves of the extremities.