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[Muli-infarct dementia].

V F Shefer

    Zhurnal Nevropatologii I Psikhiatrii Imeni S.S. Korsakova (Moscow, Russia : 1952)
    |January 1, 1985
    PubMed
    Summary

    Multiinfarction dementia, caused by multiple strokes, accounted for 11% of advanced age dementias. When combined with Alzheimer's disease, it represented 18% of cases, highlighting its significant contribution to cognitive decline.

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    [Age-related changes in interneuronal synapses in human cerebral cortex].

    Arkhiv anatomii, gistologii i embriologii·1983

    Area of Science:

    • Neurology
    • Geriatrics
    • Pathology

    Background:

    • Dementia is a significant health concern in the elderly population.
    • Distinguishing between different types of dementia is crucial for effective management.
    • Vascular dementia and Alzheimer's disease are common forms of dementia.

    Purpose of the Study:

    • To investigate the prevalence and characteristics of multiinfarction dementia in elderly patients.
    • To compare clinical and anatomical diagnoses of dementia.
    • To determine the proportion of multiinfarction dementia, both pure and mixed, in advanced age dementia cases.

    Main Methods:

    • Retrospective analysis of 255 elderly dementia cases.
    • Review of clinical diagnoses.
    • Examination of anatomical diagnoses, including the presence and location of multiple infarcts.

    Main Results:

    • Vascular dementia was the clinical diagnosis in 56% of cases.
    • Senile dementia or Alzheimer's disease was the anatomical diagnosis in 55 cases.
    • Multiinfarction dementia was diagnosed in 40 cases (11% pure, 18% mixed with Alzheimer's).
    • Multiple infarcts were predominantly localized in the subcortical ganglia (38 cases).

    Conclusions:

    • Multiinfarction dementia is a notable subtype of dementia in the elderly.
    • A significant proportion of dementia cases involve multiinfarction dementia, often in combination with Alzheimer's disease.
    • Accurate diagnosis requires consideration of both clinical and anatomical findings, particularly infarcts in subcortical areas.

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