Related Experiment Video
Updated: May 15, 2025

Systematic Approach to Identify Novel Antimicrobial and Antibiofilm Molecules from Plants' Extracts and Fractions to Prevent Dental Caries
Published on: March 31, 2021
Medicinal Plants Against Dental Caries: Research and Application of Their Antibacterial Properties
Marcela Alejandra Gloria-Garza1, Gustavo Raúl Reyna-Martínez2, Zacarías Jiménez-Salas3
1Facultad de Odontología, Universidad Autónoma de Nuevo León, Dr. Eduardo Aguirre Pequeño S/N, Monterrey 64460, NL, Mexico.
Abstract:
Dental caries remains one of the most widespread global health concerns, significantly affecting both oral and overall health. Conventional treatments typically rely on chemical-based products which, although effective, are often associated with undesirable side effects such as tooth staining, altered taste, and the development of antimicrobial resistance. As a response, plant-based natural alternatives have gained attention as promising strategies for the prevention and management of dental caries. This review highlights the antibacterial properties of medicinal plants and their potential applications in dentistry, with a particular focus on their activity against a broad range of bacteria and microorganisms involved in oral diseases. Numerous plant extracts and bioactive compounds-including polyphenols, flavonoids, and essential oils-have demonstrated antimicrobial, anti-inflammatory, and antioxidant properties that contribute to maintaining oral health. Although in vitro and in vivo studies support their therapeutic potential, clinical trials assessing long-term efficacy and safety remain scarce. Future research should prioritize the standardization of extraction methods, dosage, and formulations to facilitate the integration of these natural alternatives into conventional dental care practices.
Related Concept Videos
Combined Effects of Drugs: Synergism
Such synergistic combinations...
Antimicrobial Proteins
Interferons
Interferons (IFNs) are proteins produced by lymphocytes, macrophages, and fibroblasts infected with viruses. While IFNs cannot prevent viruses from entering and...
Defenses Against Pathogens and Herbivores
Bacterial Signaling

