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Updated: Jun 13, 2025

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Dynamic analyses of immune status in the spleen and maternal-fetal interface during gestation in mice

Kang Zhu1,2,3, Yang Yang1,2,3, Guihu Wang1,2,4

  • 1National-Local Joint Engineering Research Center of Biodiagnosis and Biotherapy, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710004, China.

Chinese Medical Journal
|May 14, 2025
PubMed
Abstract

No abstract available in PubMed .

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Development of Immunocompetence01:22

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The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
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