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Updated: May 21, 2025

Author Spotlight: Advancing Real-Time cAMP Detection in Cells Using cADDis Biosensor
06:03

Author Spotlight: Advancing Real-Time cAMP Detection in Cells Using cADDis Biosensor

Published on: March 22, 2024

791

GPCR signaling via cAMP nanodomains

Rahul Yadav1, Manuela Zaccolo1

  • 1Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, OX1 3PT, United Kingdom.

The Biochemical Journal
|May 14, 2025
PubMed
Summary

G protein-coupled receptors (GPCRs) generate cyclic adenosine monophosphate (cAMP) signals within specific cellular nanodomains. Phosphodiesterases (PDEs) regulate these localized cAMP signals, influencing cellular functions.

Keywords:
GPCRcAMP signalingcompartmentalizationphosphodiesterasesprotein kinase A

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