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Updated: May 16, 2025

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
Published on: June 16, 2020
An update on diagnosis and treatments of childhood interstitial lung diseases
Honorata Marczak1, Katarzyna Krenke1, Matthias Griese2
1Department of Pediatric Pneumology and Allergy, Medical University of Warsaw, Warsaw, Poland.
Insights
Childhood interstitial lung diseases (chILDs) are rare but serious respiratory conditions in children. This review updates diagnostic and management strategies for chILDs, emphasizing multidisciplinary care.
Area of Science:
- Pediatric Pulmonology
- Rare Diseases
- Respiratory Medicine
Background:
- Childhood interstitial lung diseases (chILDs) are rare, heterogeneous respiratory disorders.
- chILDs present with chronic respiratory symptoms and diffuse chest imaging abnormalities.
- These conditions are associated with significant morbidity and mortality in children.
Purpose of the Study:
- To provide an updated overview of diagnostic approaches for chILDs.
- To outline current management strategies for chILDs.
- To highlight the importance of multidisciplinary teams in chILD care.
Main Methods:
- This review synthesizes current knowledge on chILD diagnosis and management.
- It draws upon expertise from the European Respiratory Society Clinical Research Collaboration for chILD (ERS CRC chILD-EU).
- The review focuses on a structured, multi-step diagnostic approach and available treatment options.
Main Results:
- Diagnosis of chILDs requires a systematic, multi-step evaluation.
- Treatment options are limited, often relying on supportive care.
- Emerging diagnostic tools and therapies are continually advancing chILD care.
Conclusions:
- Comprehensive care for chILDs necessitates collaborative, multidisciplinary teams.
- Increased awareness and ongoing research are crucial for improving outcomes in chILD patients.
- This review offers updated guidance for clinicians managing these complex pediatric lung diseases.
Abstract:
Childhood interstitial lung diseases (chILDs) are rare and heterogeneous disorders associated with significant morbidity and mortality. The clinical presentation of chILD typically includes chronic or recurrent respiratory signs and symptoms with diffuse radiographic abnormalities on chest imaging. Diagnosis requires a structured, multi-step approach. Treatment options are limited, with disease-specific therapies available only in selected cases and management relying primarily on supportive care. Awareness of chILDs has been steadily increasing. New diagnoses, advanced diagnostic tests, and novel treatments are emerging each year, highlighting the importance of collaborative, multidisciplinary teams in providing comprehensive care for children and families affected by these complex conditions. On behalf of the European Respiratory Society Clinical Research Collaboration for chILD (ERS CRC chILD-EU), this review provides an updated overview of the diagnostic approach and management strategies for chILDs.
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