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Failure of Antihypertensive Treatment to Restore Normal Sympathetic Activity

Fosca Quarti-Trevano1,2, Gino Seravalle3, Rita Facchetti4

  • 1University Milano-Bicocca, Milan, Italy (F.Q.T.).

Hypertension (Dallas, Tex. : 1979)
|May 14, 2025
PubMed
Summary

Antihypertensive drugs lower blood pressure but do not normalize muscle sympathetic nerve traffic (MSNA) in essential hypertension patients. This persistent sympathetic overdrive may explain residual cardiovascular risk in treated hypertensives.

Keywords:
antihypertensive agentsblood pressuregoalheart raterisk factors

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