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Cell Type-Resolved Transcriptome of Aldosterone-Induced Atrial Myopathy and Arrhythmia

David Meral1,2, Argen Mamazhakypov1, Katharina Juncker1

  • 1Faculty of Medicine, Institute of Experimental and Clinical Pharmacology and Toxicology, (D.M., A.M., K.J., S.P., A.L.), University of Freiburg, Germany.

Hypertension (Dallas, Tex. : 1979)
|May 14, 2025
PubMed
Abstract

No abstract available in PubMed .

Keywords:
atrial fibrillationendothelial cellsheart failure, diastolicmineralocorticoidsmyocytes, cardiac

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Arrhythmia is a condition characterized by an irregular heart rhythm, with ECG changes that differ based on its origin and nature. The types of arrhythmias discussed below include atrial, junctional, and ventricular arrhythmias.Atrial ArrhythmiasPremature Atrial Complexes (PACs): PACs are early atrial beats caused by stress, caffeine, alcohol, electrolyte imbalances, hypoxia, hyperthyroidism, or certain medications (e.g., bronchodilators and decongestants). The ECG shows early P waves with an...

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