Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Glaucoma: Overview

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

[Effects of electroacupuncture at "Neiguan" (PC 6) on p38 MAPK signaling pathway in rats with cardiac hypertrophy].

Zhongguo zhen jiu = Chinese acupuncture & moxibustion·2012

Same author

Accurate measurement of oxygen consumption in children undergoing cardiac catheterization.

Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions·2012

Same author

Glutathione S-transferase polymorphisms and bone tumor risk in China.

Asian Pacific journal of cancer prevention : APJCP·2012

Same author

Systemic oxygen transport derived by using continuous measured oxygen consumption after the Norwood procedure-an interim review.

Interactive cardiovascular and thoracic surgery·2012

Same author

Discovery and optimization of 2,4-diaminoquinazoline derivatives as a new class of potent dengue virus inhibitors.

Journal of medicinal chemistry·2012

Same author

β(3)-Adrenoceptor Antagonist SR59230A Attenuates the Imbalance of Systemic and Myocardial Oxygen Transport Induced by Dopamine in Newborn Lambs.

Clinical Medicine Insights. Cardiology·2012

Same journal

Photobiomodulation Therapy for Peripheral Neuropathy in Diabetic and Cancer Patients: A Narrative Review.

Photodiagnosis and photodynamic therapy·2026

Same journal

Adaptive Contour Prediction in Postoperative OCT Imaging Using Domain-Adaptive Generative Adversarial Networks.

Photodiagnosis and photodynamic therapy·2026

Same journal

Efficacy of anti-microbial photodynamic therapy in managing herpes simplex virus: A systematic review of clinical studies.

Photodiagnosis and photodynamic therapy·2026

Same journal

Optical assessment of ocular blood flow in laser-treated diabetic retinopathy: An ocular pulse amplitude analysis.

Photodiagnosis and photodynamic therapy·2026

Same journal

Repeated low-level red-light therapy for childhood myopia: Efficacy, mechanisms, rebound effects, safety boundaries, and clinical standardization.

Photodiagnosis and photodynamic therapy·2026

Same journal

The efficacy of laser ablation combined with photodynamic therapy vs PDT for CIN2/3 in reproductive women: a prospective case-control study.

Photodiagnosis and photodynamic therapy·2026

See all related articles

Search research articles

Related Experiment Video

Updated: May 16, 2025

In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography

In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography

Published on: July 24, 2020

Advances in choroid-glaucoma structural-functional correlations using swept-source optical coherence tomography.

Ying Tang¹, Yun Zhao¹, Qiyao Wang¹

¹Department of Ophthalmology, The Second Hospital of Jilin University, Changchun 130041, China.

Photodiagnosis and Photodynamic Therapy

|May 14, 2025

Summary

This summary is machine-generated.

Glaucoma progression is linked to changes in the choroid, the eye's vascular layer. Advanced imaging techniques reveal these structural and blood flow alterations, aiding early glaucoma detection and treatment.

Keywords:

Choroid Glaucoma Optical coherence tomography Progression

More Related Videos

Determining Gender-Based Differences in Retinal and Choroidal Thickness in Underweight Individuals via Swept-Source Optical Coherence Tomography

Determining Gender-Based Differences in Retinal and Choroidal Thickness in Underweight Individuals via Swept-Source Optical Coherence Tomography

Published on: December 1, 2023

Using Optical Coherence Tomography and Optokinetic Response As Structural and Functional Visual System Readouts in Mice and Rats

Using Optical Coherence Tomography and Optokinetic Response As Structural and Functional Visual System Readouts in Mice and Rats

Published on: January 10, 2019

Related Experiment Videos

Last Updated: May 16, 2025

In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography

In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography

Published on: July 24, 2020

Determining Gender-Based Differences in Retinal and Choroidal Thickness in Underweight Individuals via Swept-Source Optical Coherence Tomography

Determining Gender-Based Differences in Retinal and Choroidal Thickness in Underweight Individuals via Swept-Source Optical Coherence Tomography

Published on: December 1, 2023

Using Optical Coherence Tomography and Optokinetic Response As Structural and Functional Visual System Readouts in Mice and Rats

Using Optical Coherence Tomography and Optokinetic Response As Structural and Functional Visual System Readouts in Mice and Rats

Published on: January 10, 2019

Area of Science:

Ophthalmology
Vascular Biology
Medical Imaging

Background:

The choroid, a vascular tissue supplying the retina, is implicated in glaucoma progression.
Its exact role is unclear due to research technique limitations.
Glaucoma is a leading cause of irreversible blindness worldwide.

Purpose of the Study:

To elucidate glaucoma pathophysiology by assessing choroidal anatomy and blood flow.
To investigate the link between choroidal changes and glaucoma progression.
To highlight the utility of swept-source optical coherence tomography (SS-OCT) in glaucoma management.

Main Methods:

Review combining swept-source optical coherence tomography (SS-OCT) findings with noninvasive angiography data.
Comprehensive assessment of choroidal anatomy and hemodynamics in glaucoma patients.
Analysis of functional and structural changes in the choroid.

Main Results:

Functional and structural choroidal changes are evident in glaucoma patients.
These changes correlate with disease progression.
The mechanism of choroidal involvement varies across different glaucoma subtypes.

Conclusions:

Choroidal alterations are significant in glaucoma pathophysiology.
SS-OCT shows potential for early glaucoma diagnosis and monitoring.
Understanding the choroid's role may lead to novel therapeutic strategies for glaucoma.