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HSC70 Promotes Breast Cancer Progression via PTEN Autophagic Degradation and PI3K/AKT/mTOR Activation

Zhengqi Wei1,2, Beichen Xie2,3, Xiangrui Meng4,5

  • 1Department of Radiology, The First Affiliated Hospital of Xinxiang Medical University, Xinxiang, China.

Molecular Carcinogenesis
|May 15, 2025
PubMed
Summary

Heat shock cognate protein 70 (HSC70) is highly expressed in breast cancer, promoting tumor growth and poor prognosis. Targeting HSC70 may offer a new therapeutic strategy for breast cancer treatment.

Keywords:
HSC70PTENautophagybreast cancercell cycle

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