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Updated: May 17, 2025

A Protocol for the Administration of Real-Time fMRI Neurofeedback Training
Published on: August 24, 2017
NINFA: Non-commercial interface for neuro-feedback acquisitions
Costanza Iester1, Clint Banzhaf2, Ahmed Eldably3,4
1University of Genoa, Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, Genoa, Italy.
Significance:
In recent years, functional near-infrared spectroscopy (fNIRS) has gained increasing attention in the field of neurofeedback. However, there is a lack of freely accessible tools for research in this area that reflect the state of the art in research and technology.
Aim:
To address this need, we introduce Non-commercial Interface for Neuro-Feedback Acquisitions (NINFA), a user-friendly and flexible freely available neurofeedback application for real-time fNIRS, which is also open to other modalities such as electroencephalography (EEG).
Approach:
NINFA was developed in MATLAB and the lab streaming layer connection offers maximum flexibility in terms of combination with different fNIRS or EEG acquisition software and hardware.
Results:
The user-friendly interface allows measurements without requiring programming expertise. New neurofeedback protocols can be easily created, saved, and retrieved. We provide an example code for real-time data preprocessing and visual feedback; however, users can customize or expand it with appropriate programming skills.
Conclusions:
NINFA enables real-time recording, analysis, and feedback of brain signals. We were able to demonstrate the stability and reliability of the computational performance of preprocessing and analysis methods in the current version. NINFA is intended as an application that can, should, and may evolve with the help of contributions from the community.
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