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Related Concept Videos

Esophageal Varices-I: Introduction01:24

Esophageal Varices-I: Introduction

52
Esophageal varices are dilated, tortuous veins which are found mainly in the submucosa of the lower esophagus but which may also appear higher up or extend into the stomach. They develop due to increased pressure in the portal venous system, often as a result of liver cirrhosis. This condition scars and damages the liver, impeding normal blood flow through the portal vein. To compensate, blood seeks alternative pathways, forming fragile new vessels (varices) in the esophagus and stomach. These...
52
Esophageal Varices-II: Clinical Features and Management01:28

Esophageal Varices-II: Clinical Features and Management

31
Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
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Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

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Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
134
Appendicitis-I: Introduction01:22

Appendicitis-I: Introduction

73
The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
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Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

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Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
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Related Experiment Video

Updated: May 17, 2025

Development of an IFN-γ ELISpot Assay to Assess Varicella-Zoster Virus-specific Cell-mediated Immunity Following Umbilical Cord Blood Transplantation
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Adult Intussusception Secondary to Varicella-Zoster Virus Infection.

Jennifer Madukaife1,2, Micah Pippin1,2, George Collins3

  • 1Family Medicine, Louisiana State University Health Sciences Center, Alexandria, USA.

Cureus
|May 15, 2025
PubMed
Summary
This summary is machine-generated.

Varicella-zoster virus (VZV) infection is linked to a rare case of intussusception. This study highlights the unusual gastrointestinal effects of VZV, emphasizing early diagnosis and further research.

Keywords:
adult small bowel intussusceptionatypical varicellavaricella vaccinevaricella zoster virus infectionvaricella-zoster (chickenpox)

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Area of Science:

  • Virology
  • Gastroenterology
  • Pediatrics

Background:

  • Varicella-zoster virus (VZV), or human herpesvirus 3, is a DNA virus causing chickenpox and shingles.
  • Gastrointestinal pathology associated with VZV is not well-documented, with effects primarily theoretical.

Observation:

  • This case report details an unusual instance of intussusception (bowel telescoping) occurring concurrently with varicella infection.
  • The presentation of intussusception in the context of VZV infection is exceptionally rare in medical literature.

Findings:

  • The study documents a rare association between VZV infection and the development of intussusception.
  • This case provides empirical evidence for a potential, albeit uncommon, link between VZV and gastrointestinal complications.

Implications:

  • Early diagnosis and prompt, specific management are crucial for patients presenting with VZV and intussusception.
  • Further research is warranted to elucidate the mechanisms underlying the association between VZV and intussusception.