Related Experiment Video
Updated: May 17, 2025
07:38
Strategies for Assessing Autistic-Like Behaviors in Mice
Published on: September 20, 2024
764
A Comprehensive Review on Plant-Based Medications and Chemical Approaches for Autism Spectrum Disorders (ASDs)
Vrish Dhwaj Ashwlayan1, Ratneshwar Kumar Ratnesh2, Divya Sharma3
1Department of Pharmaceutical Technology, Meerut Institute of Engineering and Technology, Meerut, U.P. 250005 India.
Indian Journal of Microbiology
|May 15, 2025
Summary
Dietary polyphenols show promise in managing autism spectrum disorder (ASD) symptoms by reducing inflammation and improving brain barrier function. Combining plant-based and chemical therapies may offer a more effective approach to treating ASDs.
Area of Science:
- Neuroscience
- Pharmacology
- Nutritional Science
Background:
- Autism spectrum disorder (ASD) is a lifelong neurodevelopmental condition characterized by social interaction and communication deficits, alongside restricted behaviors.
- Gastrointestinal issues in ASD patients are linked to sleep, behavioral, and psychiatric disorders.
- Existing therapeutic strategies for ASDs are diverse, including chemical and plant-based interventions.
Purpose of the Study:
- To investigate the potential of dietary polyphenols and plant-based compounds in managing ASD symptoms.
- To explore the neuro-psychopharmacological benefits of natural therapies for ASD.
- To evaluate the efficacy of combined plant-based and chemical therapeutic approaches for ASD.
Main Methods:
- Review of existing research on therapeutic modalities for ASDs.
- Analysis of the antioxidant and anti-inflammatory effects of dietary polyphenols.
- Investigation into the impact of bioactive compounds on blood-brain barrier permeability.
Main Results:
- Dietary polyphenols exhibit antioxidant and anti-inflammatory properties, potentially delaying ASD onset and aiding management.
- Plant-based therapies demonstrate neuro-psychopharmacological benefits, effectively reducing ASD-related symptoms.
- Combined plant-based and chemical interventions may offer superior therapeutic outcomes for ASDs.
Conclusions:
- Bioactive compounds, particularly dietary polyphenols, show significant potential in managing ASD symptoms.
- Plant-derived compounds offer a comprehensive approach by addressing neurological aspects and restoring neurochemical balance.
- Further clinical validation is necessary to confirm the therapeutic efficacy of these bioactive molecules in ASD management.
Keywords:
Autism spectrum disorders (ASDs)Bioactive moleculesClinical evidencesPlant-food-derivedPreclinical studiesMore Related Videos
08:42A Familiarization Protocol Facilitates the Participation of Children with ASD in Electrophysiological Research
Published on: July 31, 2017
8.2K
08:30Author Spotlight: Exploring Autism Spectrum Disorder Symptoms in Fruit Flies — Genetic Models and Behavioral Tests
Published on: September 6, 2024
1.4K
Related Concept Videos
01:19Autism Spectrum Disorder
50
Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
50
01:28Drug Therapy
32
The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
Antianxiety Medications
32
01:26Modeling in Therapy
37
Modeling, a key technique in therapy, uses observational learning to help clients acquire and practice new skills by watching therapists demonstrate desired behaviors. This approach, rooted in Albert Bandura's concept of vicarious learning, plays a significant role in therapeutic interventions for various psychological conditions, including social anxiety, ADHD, and depression.
Participant Modeling
Participant modeling involves therapists demonstrating calm and effective behaviors in...
Participant Modeling
Participant modeling involves therapists demonstrating calm and effective behaviors in...
37
01:26Psychosis: Goals of Pharmacotherapy
99
Antipsychotic drugs are a crucial treatment method for acute and chronic psychoses, bipolar illness, and behavioral disorders. The selection of these drugs depends on several factors, including the state of the disease, clinical judgment, possible drug interactions, and the patient's sensitivity to adverse effects. In immediate scenarios, such as delirium and dementia, short-term treatment with low doses of high-potency typical or atypical agents can effectively manage symptom exacerbation.
99
01:29Theoretical Approaches to Psychological Disorder
60
The development of psychological disorders, which are characterized by deviant, maladaptive, and personally distressing behaviors, has been explored through several theoretical approaches.
Biological approach
The biological approach posits that internal, organic factors are the primary causes of such disorders. This perspective emphasizes brain structure and function, genetic predispositions, and neurotransmitter imbalances. For example, schizophrenia has been associated with both genetic...
Biological approach
The biological approach posits that internal, organic factors are the primary causes of such disorders. This perspective emphasizes brain structure and function, genetic predispositions, and neurotransmitter imbalances. For example, schizophrenia has been associated with both genetic...
60
01:24Treatment Strategies for Psychological Disorders
65
Treatment approaches for psychological disorders fall into three main categories: psychological, biological, and sociocultural. Each approach targets different aspects of mental health, requiring varying levels of education and training.
Psychological therapies focus on modifying emotions, thoughts, and behaviors through talking, interpreting, listening, rewarding, challenging, and modeling. Clinical psychologists, counselors, and social workers commonly practice psychotherapy. Clinical...
Psychological therapies focus on modifying emotions, thoughts, and behaviors through talking, interpreting, listening, rewarding, challenging, and modeling. Clinical psychologists, counselors, and social workers commonly practice psychotherapy. Clinical...
65