Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Preadolescent alcohol abuse and dependence.

R Famularo, K Stone, C Popper

    The American Journal of Psychiatry
    |October 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Suspect severe gastroenteritis associated with ingestion of caterpillar setae fragments in a cat.

    Australian veterinary journal·2023
    Same author

    Decision Regret among Patients with Early-stage Lung Cancer Undergoing Radiation Therapy or Surgical Resection.

    Clinical oncology (Royal College of Radiologists (Great Britain))·2023
    Same author

    The 2019-2020 volcanic eruption of Late'iki (Metis Shoal), Tonga.

    Scientific reports·2022
    Same author

    Low Protein Intake Irrespective of Source is Associated with Higher Mortality Among Older Community-dwelling Men.

    The journal of nutrition, health & aging·2020
    Same author

    Processes of consent in research for adults with impaired mental capacity nearing the end of life: systematic review and transparent expert consultation (MORECare_Capacity statement).

    BMC medicine·2020
    Same author

    Cerebrospinal fluid opening pressure: The effect of body mass index and body composition.

    Clinical neurology and neurosurgery·2019
    Same journal

    2026 Annual Meeting: President-Elect Address.

    The American journal of psychiatry·2026
    Same journal

    2026 Annual Meeting: CEO and Medical Director's Address.

    The American journal of psychiatry·2026
    Same journal

    Reports to the Membership.

    The American journal of psychiatry·2026
    Same journal

    Convergent Metabolic Dysregulations But Divergent Contributing Pathways Across Severe Mental Disorders: The Power of Combining Genetics and Metabolomics.

    The American journal of psychiatry·2026
    Same journal

    2026 Annual Meeting: Presidential Address.

    The American journal of psychiatry·2026
    Same journal

    Represcribing Previously Used Antipsychotics: Response to So.

    The American journal of psychiatry·2026
    See all related articles

    Early alcohol abuse in children, diagnosed by age 13, is linked to major affective disorders. Many children with bipolar disorder showed positive responses to psychotropic medications.

    Area of Science:

    • Child and Adolescent Psychiatry
    • Addiction Medicine
    • Genetic Psychiatry

    Background:

    • Early-onset alcohol use disorders (AUD) in children are increasingly recognized.
    • Family history of alcoholism and affective disorders, particularly bipolar disorder, is common in affected youth.
    • Understanding the developmental trajectory of AUD is crucial for early intervention.

    Observation:

    • Documented 10 pediatric cases meeting DSM-III criteria for alcohol abuse or dependence by age 13.
    • One case report highlighted a family history of affective disorder (especially bipolar disorder) and alcoholism.
    • Most children diagnosed with bipolar disorder demonstrated positive responses to psychotropic treatments.

    Findings:

    • A significant association exists between early-onset alcohol abuse and the subsequent development of major affective disorders in adolescence.

    Related Experiment Videos

  • The presence of familial affective disorders may predispose children to early-onset AUD.
  • Psychotropic medication appears effective for managing comorbid bipolar disorder in this population.

    • Implications:

    • Suggests a potential shared etiology or developmental pathway between early-onset AUD and adolescent-onset bipolar disorder.
    • Highlights the importance of screening for AUD in children with a family history of bipolar disorder.
    • Informs targeted interventions and treatment strategies for at-risk youth.