Relationship Between Objective Performance and Patient-Reported Outcomes Measurement Information System Physical...

Area of Science:

• Neurology
• Rehabilitation Medicine
• Health Outcomes Research

Background:

• The link between subjective physical function (PF) and objective performance in stroke survivors is not well understood.
• Investigating how various health domains impact the PF-TUG relationship is crucial for accurate patient assessment.

Purpose of the Study:

• To examine the correlation between Patient-Reported Outcomes Measurement Information System (PROMIS) PF and the Timed Up and Go (TUG) test in stroke patients.
• To determine how other self-reported health outcomes mediate this relationship.

Main Methods:

• Retrospective cohort study of 432 stroke patients within 90 days post-stroke.
• Analysis of correlations between PROMIS PF and TUG, stratified by other PROMIS scales and Quality of Life in Neurological Disorders measures.
• Structural equation modeling to assess the influence of health domains on the PROMIS PF-TUG relationship.

Main Results:

• A moderate correlation (r=-0.47) was found between PROMIS PF and TUG.
• Fatigue (r=-0.53) and social satisfaction (r=0.53) showed the strongest correlations with PROMIS PF.
• Both social roles and fatigue significantly mediated the relationship between PROMIS PF and TUG.

Conclusions:

• The correlation between self-reported PF and TUG performance in stroke patients is moderately influenced by fatigue and social satisfaction.
• Broader health dimensions, beyond physical capacity, are important for interpreting patient-reported PF scores in stroke survivors.