Related Experiment Video

Updated: Oct 21, 2026

In vitro Assessment of Myocardial Protection following Hypothermia-Preconditioning in a Human Cardiac Myocytes Model
08:22

In vitro Assessment of Myocardial Protection following Hypothermia-Preconditioning in a Human Cardiac Myocytes Model

Published on: October 27, 2020

[The effect of rewarming of stored blood on plasma value and erythrocytes]

H Stephan, R Larsen, H Sonntag

    Der Anaesthesist
    |July 1, 1985
    PubMed

    30 units of stored blood of different age were rewarmed from 4 degrees C to 32 degrees C by microwave blood-warmer Infusotherm 407. The resulting damage to blood components and change of function of erythrocytes were compared with those caused by storage of CPD-blood. Dependent on the age of stored blood we found considerable increases in the plasma-levels of potassium, lactate, and free haemoglobin. Compared with cold CPD-blood rewarming of stored blood produced a 7% increase in lactate and a 8% increase in free haemoglobin. There were no changes in platelet and erythrocyte counts, haematocrit, plasma-levels of haemoglobin, electrolytes, cholesterol, blood viscosity, osmotic resistance, and oxygen-binding capacity. As damage of stored blood produced by warming is minimal compared with that produced by storage, the Infusotherm 407 is considered to be a clinically useful blood-warmer.

    More Related Videos

    Cryopreservation and Bioenergetic Evaluation of Human Peripheral Blood Mononuclear Cells04:10

    Cryopreservation and Bioenergetic Evaluation of Human Peripheral Blood Mononuclear Cells

    Published on: October 20, 2023

    Real-Time, Noninvasive Evaluation of Mitochondrial Function Using Resonance Raman Spectroscopy08:27

    Real-Time, Noninvasive Evaluation of Mitochondrial Function Using Resonance Raman Spectroscopy

    Published on: August 7, 2026

    Related Concept Videos

    Blood Transfusion and Agglutination02:45

    Blood Transfusion and Agglutination

    Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
    History
    The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
    Erythropoiesis01:14

    Erythropoiesis

    Red blood cells  (RBCs) transport oxygen to all body tissues. These cells survive only for 120 days and then need to be replenished. Erythropoiesis is the process of RBC production. In healthy individuals, erythropoiesis ensures all tissues are amply supplied with oxygen. In addition, blood loss due to injury leads to a drop in the physiological oxygen level that will cause erythropoiesis. Any defect in erythropoiesis leads to several physiological disorders, including thalassemia, anemia, and...
    Lifecycle of Erythrocytes01:22

    Lifecycle of Erythrocytes

    Erythrocytes, also known as red blood cells, constantly move through blood capillaries. As a result, they damage their plasma membrane due to the continuous friction. Typically, after 100 to 120 days, erythrocytes become rigid and fragile as they wear out. As they pass through small vessels in the spleen and liver, they can get trapped and break apart into fragments.
    The resident phagocytic macrophages deal with these damaged cells by engulfing them and separating their globin and heme groups.
    Factors Affecting Erythropoiesis01:24

    Factors Affecting Erythropoiesis

    The cardiovascular system regulates the number of erythrocytes in the bloodstream to ensure optimal oxygen transport. It also prevents over-proliferation of these cells, which helps to maintain blood viscosity and flow rate.
    Several factors influence the erythrocyte production rate, with tissue oxygen level being among the most critical. Intense exercise or high altitudes can cause tissue hypoxia, which triggers the kidneys to release more erythropoietin (EPO) into the bloodstream.
    EPO then...
    Oxygen Transport in the Blood01:27

    Oxygen Transport in the Blood

    Hemoglobin (Hb) is a crucial molecule in the human body, consisting of four polypeptide chains, each bound to an iron-containing heme group. This unique structure enables hemoglobin to bind to oxygen, with each molecule capable of combining with four molecules of oxygen, leading to rapid and reversible oxygen loading. When fully loaded with oxygen, it is called oxyhemoglobin, while hemoglobin that has released oxygen is called reduced hemoglobin or deoxyhemoglobin. As hemoglobin binds oxygen,...