Related Experiment Video

Updated: May 21, 2025

Laser-heating and Radiance Spectrometry for the Study of Nuclear Materials in Conditions Simulating a Nuclear Power Plant Accident
09:18

Laser-heating and Radiance Spectrometry for the Study of Nuclear Materials in Conditions Simulating a Nuclear Power Plant Accident

Published on: December 14, 2017

10.3K

A nuclear house divided

Timothy J Mitchison1, William T Sullivan2

  • 1Department of Systems Biology, Harvard Medical School, Boston, MA, USA.

Science (New York, N.Y.)
|May 15, 2025
PubMed

Insights

Fungal plant pathogens can have different chromosome numbers in their multiple nuclei. This variation impacts pathogen evolution and disease development.

Area of Science:

  • Mycology
  • Plant Pathology
  • Genetics

Background:

  • Fungal pathogens pose significant threats to global agriculture.
  • Understanding the genetic makeup of these pathogens is crucial for disease management.
  • Nuclear and chromosomal variations are observed in various fungal species.

Purpose of the Study:

  • To investigate the phenomenon of varying chromosome distributions in fungal plant pathogens.
  • To explore the implications of aneuploidy in fungal pathogenicity.

Main Methods:

  • Comparative genomics
  • Fluorescence in situ hybridization (FISH)
  • Quantitative PCR (qPCR)

Main Results:

  • Demonstrated aneuploidy in multiple nuclei of specific fungal plant pathogens.
  • Identified significant variations in chromosome number and content across different nuclei within the same fungal isolate.
  • Correlated chromosomal variations with specific pathogenic traits.

Conclusions:

  • The study confirms that fungal plant pathogens exhibit diverse chromosomal distributions within their nuclei.
  • This genetic plasticity may contribute to adaptation and virulence.
  • Further research into nuclear dynamics can reveal novel targets for antifungal strategies.

More Related Videos

Spatiotemporally Controlled Nuclear Translocation of Guests in Living Cells Using Caged Molecular Glues as Photoactivatable Tags10:10

Spatiotemporally Controlled Nuclear Translocation of Guests in Living Cells Using Caged Molecular Glues as Photoactivatable Tags

Published on: January 17, 2019

10.4K
Author Spotlight: Advancing In Vitro Blood Cell Production with Single-Cell Multiomics and Functional Genomics04:11

Author Spotlight: Advancing In Vitro Blood Cell Production with Single-Cell Multiomics and Functional Genomics

Published on: March 15, 2024

1000

Related Concept Videos

Nuclear Fission02:50

Nuclear Fission

Many heavier elements with smaller binding energies per nucleon can decompose into more stable elements that have intermediate mass numbers and larger binding energies per nucleon—that is, mass numbers and binding energies per nucleon that are closer to the “peak” of the binding energy graph near 56. Sometimes neutrons are also produced. This decomposition of a large nucleus into smaller pieces is called fission. The breaking is rather random with the formation of a large...
9.5K
Nuclear Power02:36

Nuclear Power

Controlled nuclear fission reactions are used to generate electricity. Any nuclear reactor that produces power via the fission of uranium or plutonium by bombardment with neutrons has six components: nuclear fuel consisting of fissionable material, a nuclear moderator, a neutron source, control rods, reactor coolant, and a shield and containment system.
Nuclear Fuels
Nuclear fuel consists of a fissile isotope, such as uranium-235, which must be present in sufficient quantity to provide a...
7.6K
Nuclear Fusion02:45

Nuclear Fusion

The process of converting very light nuclei into heavier nuclei is also accompanied by the conversion of mass into large amounts of energy, a process called fusion. The principal source of energy in the sun is a net fusion reaction in which four hydrogen nuclei fuse and ultimately produce one helium nucleus and two positrons.
A helium nucleus has a mass that is 0.7% less than that of four hydrogen nuclei; this lost mass is converted into energy during the fusion. This reaction produces about...
17.2K
Nuclear Transmutation03:20

Nuclear Transmutation

Nuclear transmutation is the conversion of one nuclide into another. It can occur by the radioactive decay of a nucleus, or the reaction of a nucleus with another particle. The first manmade nucleus was produced in Ernest Rutherford’s laboratory in 1919 by a transmutation reaction, the bombardment of one type of nuclei with other nuclei or with neutrons. Rutherford bombarded nitrogen-14 atoms with high-speed α particles from a natural radioactive isotope of radium and observed...
17.3K
Nuclear Stability03:18

Nuclear Stability

Protons and neutrons, collectively called nucleons, are packed together tightly in a nucleus. With a radius of about 10−15 meters, a nucleus is quite small compared to the radius of the entire atom, which is about 10−10 meters. Nuclei are extremely dense compared to bulk matter, averaging 1.8 × 1014 grams per cubic centimeter. If the earth’s density were equal to the average nuclear density, the earth’s radius would be only about 200 meters.
To hold positively charged...
18.4K
Introduction to Nuclear Reprogramming01:14

Introduction to Nuclear Reprogramming

Nuclear reprogramming is the process of switching gene expression of one cell type to that of another cell type, usually from a differentiated cell state to an undifferentiated cell state. Differentiation occurs during processes such as development and morphogenesis, tissue regeneration, and malignancy. Cells can also be artificially induced to reprogram their gene expression by techniques such as nuclear transfer, induced pluripotency, and cell fusion. Such techniques have many applications in...
1.9K