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Updated: May 17, 2025

Subretinal Implantation of RPE on a Carrier in Minipigs: Guidelines for Preoperative Preparations, Surgical Techniques, and Postoperative Care

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Rate and Rationale for Vitrectomy after Pneumatic Retinopexy.

Bradley T Smith¹, M Zia Siddiqui¹, Gautam Vangipuram²

¹The Retina Institute of St. Louis, St. Louis, Missouri.

Ophthalmology. Retina

|May 15, 2025

Summary

This summary is machine-generated.

Nearly 10% of eyes treated for retinal detachment (RD) with pneumatic retinopexy (PnR) required a subsequent vitrectomy for non-RD reasons. Visual acuity outcomes were comparable to eyes needing surgical repair for RD.

Keywords:

Iris Pneumatic retinopexy Retinal detachment Scleral Buckle Vitrectomy

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Published on: February 15, 2022

Area of Science:

Ophthalmology
Retinal Surgery
Public Health

Background:

Pneumatic retinopexy (PnR) is a common surgical technique for retinal detachment (RD) repair.
Pars plana vitrectomy (PPV) is another surgical option for RD and other retinal conditions.
Understanding the rate and reasons for PPV after PnR is crucial for patient counseling and surgical planning.

Purpose of the Study:

To determine the incidence of pars plana vitrectomy (PPV) after pneumatic retinopexy (PnR) for retinal detachment (RD) repair.
To identify the indications for non-RD PPV following PnR.
To compare visual acuity (VA) outcomes between eyes undergoing non-RD PPV and other management strategies.

Main Methods:

Retrospective, nonrandomized comparative study using the IRIS® Registry (04/01/2013 to 12/31/2021).
Inclusion/exclusion criteria applied via billing codes to define three groups: Group 1 (non-RD PPV post-PnR), Group 2 (no surgery post-PnR), Group 3 (RD requiring surgical repair post-PnR).
Analysis of subsequent PPV indications, follow-up duration, and visual acuity (VA).

Main Results:

9,107 eyes were analyzed; 9.4% (556 eyes) required a non-RD PPV after PnR reattachment.
Common indications for non-RD PPV included internal limiting membrane (25.7%) and epiretinal membrane removal (18.3%).
Final VA was similar to eyes requiring surgical RD repair (Group 3) but lower than eyes not needing further surgery (Group 2); follow-up was longer than both groups.

Conclusions:

Approximately 1 in 10 eyes treated with PnR for RD may necessitate a subsequent non-RD PPV.
Visual outcomes after non-RD PPV are comparable to those requiring surgical RD repair.
The potential need for PPV should be discussed during patient counseling for PnR.