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Updated: May 23, 2025

A Galvanotaxis Assay for Analysis of Neural Precursor Cell Migration Kinetics in an Externally Applied Direct Current Electric Field
Published on: October 13, 2012
Is there a relationship between embryonic bioelectric currents and differentiation waves?
1Gulf Specimen Marine Laboratory & Aquarium, 222 Clark Drive, Panacea, FL, 32346, USA; Retired from University of Manitoba, Winnipeg, MB, Canada.
Abstract:
Differentiation waves usually spread in embryonic epithelia until they reach boundaries whose stopping power has been unexplained. Bioelectricity in embryos has two ranges: cell-to-cell and long-range. It is postulated here that the long-range component somehow alters gap junctions and/or intermediate filaments, creating the boundaries for the trajectories of differentiation waves. A combined EIT (Electric Impedance Tomography)/visual microscope is proposed to investigate this proposed correlation.
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