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Updated: May 17, 2025

A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy
Forecasting emerging trends in transfusion medicine through complex network analysis of scholars' research
Feng Lin1, Xu He1, Huifang Zhang1
1Institute of Blood Transfusion, Chinese Academy of Medical Science and Peking Union Medical College, Chengdu, People's Republic of China.
Background And Objectives:
This study aimed to analyse and predict emerging trends in transfusion medicine using complex network analysis of high-impact global scholar rankings.
Materials And Methods:
Network analysis was employed to uncover research trends, identify central research directions and map knowledge networks. The analytical hierarchy process was used to evaluate potential future research trajectories. The Kolmogorov-Smirnov test assessed network centrality differences, with cross-validation performed using the Association for the Advancement of Blood & Biotherapies (AABB) and the International Society of Blood Transfusion (ISBT) conference themes.
Results:
Clinical transfusion is the central theme, with transfusion management, evaluation and specific transfusions like platelet and plasma gaining prominence. Blood safety evolved into a standalone domain, while immunohaematology and cell therapy represent emerging trends. Innovations in blood storage, transfusion technology and omics insights are shaping future directions. Notably, despite global healthcare impacts, COVID-19 has not significantly redirected transfusion medicine research.
Conclusion:
The transfusion medicine landscape demonstrates stability in its core framework while increasingly focusing on emerging areas such as personalized therapies, platelet transfusion and cell-based treatments.
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