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Metabolic syndrome and pigmentation: a review of the connecting link
Abheek Sil1, Shreya Poddar2, Anupam Das3
1Department of Dermatology, Venereology, and Leprosy, PKG Medical College and Hospital, Kolkata, India.
Abstract:
There is an ongoing interest regarding the association of metabolic syndrome (MetS) and skin diseases. However, the link between MetS and pigmentation has not been extensively explored. In this review, we undertake a detailed discussion on the existing literature on this topic, the various implicated pathomechanisms and/or molecular pathways, and highlight scope for further scientific exploration. A better understanding of the relationship between MetS and disorders of pigmentation contributes to early diagnosis and prevention, as well as providing clues for developing novel therapeutic strategies.
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