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Epidemiological Analysis of the Decline of Myocarditis Burden - China, 1992-2021

Shengnan Wang1, Xiangfeng Zhu1, Yanwu Nie1

  • 1School of Public Health, Jiangxi Provincial Key Laboratory of Disease Prevention and Public Health, Jiangxi Medical College, Nanchang University, Nanchang 330006, China.

China CDC Weekly
|May 16, 2025
PubMed

Insights

Myocarditis burden in China is decreasing, but mortality rates exceed global averages, particularly in males and older/younger age groups. Prevention efforts should target these high-risk populations.

Area of Science:

  • Cardiovascular Disease Epidemiology
  • Public Health Research

Background:

  • Myocarditis is a significant cardiovascular condition with potential for severe complications.
  • Previous data indicated an increasing trend in myocarditis cases and deaths in China, contributing to disease burden.

Purpose of the Study:

  • To analyze the epidemiological trends and burden of myocarditis in China.
  • To identify risk factors associated with myocarditis mortality.
  • To inform public health strategies for myocarditis prevention and management.

Main Methods:

  • Analysis of national health data to assess myocarditis incidence, mortality, and disability-adjusted life years (DALYs).
  • Calculation of age-standardized rates (ASIR, ASMR, DALYs) for comparison.
  • Identification of demographic and temporal risk factors for myocarditis mortality.

Main Results:

  • The overall burden of myocarditis in China shows a downward trend.
  • However, age-standardized mortality rate (ASMR) and DALYs rate for myocarditis remain higher than the global average.
  • Males, individuals younger than 5 years or older than 70 years, and earlier birth cohorts (pre-1957) were identified as high-risk groups for myocarditis mortality.

Conclusions:

  • Despite a decreasing overall burden, myocarditis poses a significant public health challenge in China.
  • Targeted prevention and treatment strategies are crucial, focusing on high-risk demographics.
  • Public health interventions should prioritize males and individuals in the youngest and oldest age groups, alongside proactive health education.
Abstract

Keywords:
APC modelEpidemic characteristicsJoinpoint modelMyocarditis

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