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Histological effect of fluoride varnishes on teeth with caries in the white spot phase: An in vitro study
Margot Margarita Gutiérrez-Ilave1, Rocío Del Pilar Ríos-León2, Antonia Castro-Rodríguez1
1DDS. MSc., Professor of the Department of Preventive and Social Stomatology, Faculty of Dentistry, Universidad Nacional Mayor de San Marcos. Lima, Perú.
Background:
The aim of this study was to compare the histological remineralization effects of two fluoride varnishes on artificially produced caries lesions in young permanent teeth.
Material And Methods:
Twenty longitudinal sections of premolars with artificially produced white spot lesions and evaluated with a polarised light microscope. The sample consisted of 20 tooth fragments, which were divided and assigned to two groups: The first group with application of Clinpro TM White Varnish (20 tooth sections) and the second, with MI Varnish TM (20 tooth sections) subjected for 6 days to conditions similar to the oral cavity. The sections were then re-evaluated by calculating the lesion depth and remineralization area (Image J software). Student' s t-test was used to analyse the data.
Results:
MI Varnish TM fluoride varnish achieved a greater remineralization area than Clinpro TM White Varnish (838042.6±140359.3 μm2 and 678313.8±137265.7μm2, respectively), with a statistically significant difference (p<0.05).
Conclusions:
MI Varnish TM had a better effect than Clinpro TM White Varnish in remineralizing lesions, in vitro, in the enamel of young permanent teeth with caries in the white-stained phase. Key words:Fluorides varnishes, histological effect, dental remineralization, polarised light microscope.

